Virus Dataset Detail

> Detail information for each sample

Dataset Information
Accession GSE165708
Status 2021/9/3
Title Epigenetic impairment and blunted transcriptional response to Mycobacterium tuberculosis of alveolar macrophages from persons living with HIV (RNA-Seq)
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Persons living with HIV (PLWH) are at increased risk of tuberculosis (TB). HIV-associated TB is mainly the result of recent infection with Mycobacterium tuberculosis (Mtb) followed by rapid progression to disease. Alveolar macrophages (AM) are the first cells of the innate immune system that engage Mtb, but how HIV and antiretroviral therapy (ART) impact on the anti-mycobacterial response of AM is not known. In this study AM were challenged in vitro with Mtb, and their epigenetic and transcriptomic responses were determined for PLWH receiving ART, control subjects who were HIV-free (HC) and subjects who received pre-exposure prophylaxis (PrEP) with ART to prevent HIV infection. Compared to HC subjects’ response to Mtb, we showed that AM isolated from PLWH and PrEP subjects displayed substantially weaker transcriptomic response and no significant changes in their chromatin state. These findings revealed a previously unknown adverse effect of ART.
Samples
GSM ID Sample info Characteristics Description
GSM5048562 RNA-Seq Healthy control sample 11, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 27;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 439;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/11/29;mtb challenged: no;rin: 10;average library size: 311;sequencing run: centre2_batch2;lane: L5 Healthy control sample 11, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC11.MTB.0_RNA_R1_quant.sf
GSM5048563 RNA-Seq Healthy control sample 11, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 27;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 439;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/11/29;mtb challenged: yes;rin: 9.8;average library size: 312;sequencing run: centre2_batch2;lane: L5 Healthy control sample 11, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC11.MTB.1_RNA_R1_quant.sf
GSM5048564 RNA-Seq Healthy control sample 12, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 40;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1263;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/12/13;mtb challenged: no;rin: 9.7;average library size: 333;sequencing run: centre1_batch2;lane: L1 Healthy control sample 12, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC12.MTB.0_RNA_R1_quant.sf
GSM5048565 RNA-Seq Healthy control sample 12, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 40;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1263;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/12/13;mtb challenged: yes;rin: 10;average library size: 328;sequencing run: centre1_batch2;lane: L1 Healthy control sample 12, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC12.MTB.1_RNA_R1_quant.sf
GSM5048566 RNA-Seq Healthy control sample 13, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: F;age: 31;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 871;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/12/12;mtb challenged: no;rin: 9.8;average library size: 356;sequencing run: centre1_batch2;lane: L1 Healthy control sample 13, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC13.MTB.0_RNA_R1_quant.sf
GSM5048567 RNA-Seq Healthy control sample 13, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: F;age: 31;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 871;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/12/12;mtb challenged: yes;rin: 10;average library size: 317;sequencing run: centre1_batch2;lane: L1 Healthy control sample 13, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC13.MTB.1_RNA_R1_quant.sf
GSM5048568 RNA-Seq Healthy control sample 14, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: F;age: 40;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1023;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: yes;bal sampling date: 2017/12/20;mtb challenged: no;rin: 10;average library size: 327;sequencing run: centre1_batch2;lane: L1 Healthy control sample 14, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC14.MTB.0_RNA_R1_quant.sf
GSM5048569 RNA-Seq Healthy control sample 14, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: F;age: 40;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1023;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: yes;bal sampling date: 2017/12/20;mtb challenged: yes;rin: 10;average library size: 377;sequencing run: centre1_batch2;lane: L1 Healthy control sample 14, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC14.MTB.1_RNA_R1_quant.sf
GSM5048570 RNA-Seq Healthy control sample 15, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: F;age: 41;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 843;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/01/17;mtb challenged: no;rin: 9.7;average library size: 325;sequencing run: centre1_batch2;lane: L4 Healthy control sample 15, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC15.MTB.0_RNA_R1_quant.sf
GSM5048571 RNA-Seq Healthy control sample 15, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: F;age: 41;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 843;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/01/17;mtb challenged: yes;rin: 9.7;average library size: 315;sequencing run: centre1_batch2;lane: L4 Healthy control sample 15, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC15.MTB.1_RNA_R1_quant.sf
GSM5048572 RNA-Seq Healthy control sample 16, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: F;age: 37;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: yes;cd4 count: 1249;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/02/21;mtb challenged: no;rin: 9.4;average library size: 317;sequencing run: centre1_batch2;lane: L5 Healthy control sample 16, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC16.MTB.0_RNA_R1_quant.sf
GSM5048573 RNA-Seq Healthy control sample 16, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: F;age: 37;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: yes;cd4 count: 1249;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/02/21;mtb challenged: yes;rin: 9.8;average library size: 313;sequencing run: centre1_batch2;lane: L5 Healthy control sample 16, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC16.MTB.1_RNA_R1_quant.sf
GSM5048574 RNA-Seq Healthy control sample 18, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 27;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 826;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/06/20;mtb challenged: no;rin: 9;average library size: 317;sequencing run: centre2_batch1;lane: L3 Healthy control sample 18, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC18.MTB.0_RNA_R1_quant.sf
GSM5048575 RNA-Seq Healthy control sample 18, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 27;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 826;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/06/20;mtb challenged: yes;rin: 8.9;average library size: 316;sequencing run: centre2_batch1;lane: L3 Healthy control sample 18, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC18.MTB.1_RNA_R1_quant.sf
GSM5048576 RNA-Seq Healthy control sample 19, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 53;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 692;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/09/19;mtb challenged: no;rin: 9.7;average library size: 333;sequencing run: centre1_batch3;lane: L2 Healthy control sample 19, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC19.MTB.0_RNA_R1_quant.sf
GSM5048577 RNA-Seq Healthy control sample 19, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 53;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 692;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/09/19;mtb challenged: yes;rin: 9.5;average library size: 329;sequencing run: centre1_batch3;lane: L2 Healthy control sample 19, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC19.MTB.1_RNA_R1_quant.sf
GSM5048578 RNA-Seq Healthy control sample 20, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Asian;Sex: M;age: 34;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 545;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/09/25;mtb challenged: no;rin: 9.7;average library size: 328;sequencing run: centre1_batch3;lane: L2 Healthy control sample 20, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC20.MTB.0_RNA_R1_quant.sf
GSM5048579 RNA-Seq Healthy control sample 20, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Asian;Sex: M;age: 34;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 545;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/09/25;mtb challenged: yes;rin: 9.6;average library size: 328;sequencing run: centre1_batch3;lane: L2 Healthy control sample 20, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC20.MTB.1_RNA_R1_quant.sf
GSM5048580 RNA-Seq Healthy control sample 21, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 57;medical.history: hypertension, type.2.diabetes;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1077;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/10/12;mtb challenged: no;rin: 9.6;average library size: 325;sequencing run: centre1_batch4;lane: L1 Healthy control sample 21, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC21.MTB.0_RNA_R1_quant.sf
GSM5048581 RNA-Seq Healthy control sample 21, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 57;medical.history: hypertension, type.2.diabetes;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1077;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/10/12;mtb challenged: yes;rin: 9.2;average library size: 326;sequencing run: centre1_batch4;lane: L1 Healthy control sample 21, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC21.MTB.1_RNA_R1_quant.sf
GSM5048582 RNA-Seq Healthy control sample 22, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: F;age: 42;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1248;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/10/12;mtb challenged: no;rin: 9.5;average library size: 326;sequencing run: centre1_batch4;lane: L1 Healthy control sample 22, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC22.MTB.0_RNA_R1_quant.sf
GSM5048583 RNA-Seq Healthy control sample 22, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: F;age: 42;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1248;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/10/12;mtb challenged: yes;rin: 9.6;average library size: 326;sequencing run: centre1_batch4;lane: L1 Healthy control sample 22, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC22.MTB.1_RNA_R1_quant.sf
GSM5048584 RNA-Seq Pre-exposure prophylaxis sample 23, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 65;medical.history: fibromyalgia;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 819;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2017;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/10/30;mtb challenged: no;rin: 9.9;average library size: 330;sequencing run: centre1_batch3;lane: L1 Pre-exposure prophylaxis sample 23, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP23.MTB.0_RNA_R1_quant.sf
GSM5048585 RNA-Seq Pre-exposure prophylaxis sample 23, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 65;medical.history: fibromyalgia;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 819;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2017;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/10/30;mtb challenged: yes;rin: 9.8;average library size: 330;sequencing run: centre1_batch3;lane: L1 Pre-exposure prophylaxis sample 23, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP23.MTB.1_RNA_R1_quant.sf
GSM5048586 RNA-Seq Pre-exposure prophylaxis sample 25, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 28;medical.history: attention.deficit.hyperactivity.disorder, depression;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 575;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/11/07;mtb challenged: no;rin: 10;average library size: 329;sequencing run: centre1_batch3;lane: L1 Pre-exposure prophylaxis sample 25, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP25.MTB.0_RNA_R1_quant.sf
GSM5048587 RNA-Seq Pre-exposure prophylaxis sample 25, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 28;medical.history: attention.deficit.hyperactivity.disorder, depression;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 575;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/11/07;mtb challenged: yes;rin: 9.9;average library size: 328;sequencing run: centre1_batch3;lane: L1 Pre-exposure prophylaxis sample 25, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP25.MTB.1_RNA_R1_quant.sf
GSM5048588 RNA-Seq Pre-exposure prophylaxis sample 26, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 25;medical.history: chronic.alcoholism;sexually transmitted infections: Syphilis RPR+;quantiferon tb reagent: no;cd4 count: 835;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2015;recreational drugs: cannabis;cigarette smoker: no;bal sampling date: 2018/11/07;mtb challenged: no;rin: 9.8;average library size: 327;sequencing run: centre1_batch3;lane: L2 Pre-exposure prophylaxis sample 26, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP26.MTB.0_RNA_R1_quant.sf
GSM5048589 RNA-Seq Pre-exposure prophylaxis sample 26, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 25;medical.history: chronic.alcoholism;sexually transmitted infections: Syphilis RPR+;quantiferon tb reagent: no;cd4 count: 835;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2015;recreational drugs: cannabis;cigarette smoker: no;bal sampling date: 2018/11/07;mtb challenged: yes;rin: 9.8;average library size: 327;sequencing run: centre1_batch3;lane: L2 Pre-exposure prophylaxis sample 26, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP26.MTB.1_RNA_R1_quant.sf
GSM5048590 RNA-Seq Pre-exposure prophylaxis sample 27, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Hispanic;Sex: M;age: 36;medical.history: None;sexually transmitted infections: chlamydia PCR+ and gonorrhea PCR+;quantiferon tb reagent: no;cd4 count: 961;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2014;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/11/21;mtb challenged: no;rin: 9.9;average library size: 330;sequencing run: centre1_batch3;lane: L2 Pre-exposure prophylaxis sample 27, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP27.MTB.0_RNA_R1_quant.sf
GSM5048591 RNA-Seq Pre-exposure prophylaxis sample 27, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Hispanic;Sex: M;age: 36;medical.history: None;sexually transmitted infections: chlamydia PCR+ and gonorrhea PCR+;quantiferon tb reagent: no;cd4 count: 961;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2014;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/11/21;mtb challenged: yes;rin: 9.8;average library size: 323;sequencing run: centre1_batch3;lane: L2 Pre-exposure prophylaxis sample 27, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP27.MTB.1_RNA_R1_quant.sf
GSM5048592 RNA-Seq Pre-exposure prophylaxis sample 28, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 60;medical.history: hypertension, diabetes, attention.deficit.hyperactivity.disorder;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1254;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: no;cigarette smoker: yes;bal sampling date: 2018/11/21;mtb challenged: no;rin: 9.6;average library size: 320;sequencing run: centre1_batch3;lane: L2 Pre-exposure prophylaxis sample 28, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP28.MTB.0_RNA_R1_quant.sf
GSM5048593 RNA-Seq Pre-exposure prophylaxis sample 28, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 60;medical.history: hypertension, diabetes, attention.deficit.hyperactivity.disorder;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1254;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: no;cigarette smoker: yes;bal sampling date: 2018/11/21;mtb challenged: yes;rin: 9.5;average library size: 325;sequencing run: centre1_batch3;lane: L2 Pre-exposure prophylaxis sample 28, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP28.MTB.1_RNA_R1_quant.sf
GSM5048594 RNA-Seq Pre-exposure prophylaxis sample 29, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: North african;Sex: M;age: 37;medical.history: None;sexually transmitted infections: chlamydia PCR+;quantiferon tb reagent: yes;cd4 count: 981;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2013;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/12/03;mtb challenged: no;rin: 9.5;average library size: 327;sequencing run: centre1_batch4;lane: L1 Pre-exposure prophylaxis sample 29, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP29.MTB.0_RNA_R1_quant.sf
GSM5048595 RNA-Seq Pre-exposure prophylaxis sample 29, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: North african;Sex: M;age: 37;medical.history: None;sexually transmitted infections: chlamydia PCR+;quantiferon tb reagent: yes;cd4 count: 981;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2013;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/12/03;mtb challenged: yes;rin: 9.7;average library size: 325;sequencing run: centre1_batch4;lane: L1 Pre-exposure prophylaxis sample 29, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP29.MTB.1_RNA_R1_quant.sf
GSM5048596 RNA-Seq Pre-exposure prophylaxis sample 30, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 30;medical.history: depression;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 847;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/12/03;mtb challenged: no;rin: 9.6;average library size: 327;sequencing run: centre1_batch4;lane: L1 Pre-exposure prophylaxis sample 30, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP30.MTB.0_RNA_R1_quant.sf
GSM5048597 RNA-Seq Pre-exposure prophylaxis sample 30, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 30;medical.history: depression;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 847;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/12/03;mtb challenged: yes;rin: 9.7;average library size: 333;sequencing run: centre1_batch4;lane: L1 Pre-exposure prophylaxis sample 30, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP30.MTB.1_RNA_R1_quant.sf
GSM5048598 RNA-Seq Pre-exposure prophylaxis sample 31, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 36;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1163;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/12/21;mtb challenged: no;rin: 8.9;average library size: 355;sequencing run: centre1_batch4;lane: L2 Pre-exposure prophylaxis sample 31, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP31.MTB.0_RNA_R1_quant.sf
GSM5048599 RNA-Seq Pre-exposure prophylaxis sample 31, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 36;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1163;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/12/21;mtb challenged: yes;rin: 9.4;average library size: 327;sequencing run: centre1_batch4;lane: L2 Pre-exposure prophylaxis sample 31, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP31.MTB.1_RNA_R1_quant.sf
GSM5048600 RNA-Seq Pre-exposure prophylaxis sample 32, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 36;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1069;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2017;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/12/21;mtb challenged: no;rin: 9.7;average library size: 334;sequencing run: centre1_batch4;lane: L2 Pre-exposure prophylaxis sample 32, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP32.MTB.0_RNA_R1_quant.sf
GSM5048601 RNA-Seq Pre-exposure prophylaxis sample 32, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 36;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1069;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2017;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/12/21;mtb challenged: yes;rin: 9.6;average library size: 325;sequencing run: centre1_batch4;lane: L2 Pre-exposure prophylaxis sample 32, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP32.MTB.1_RNA_R1_quant.sf
GSM5048602 RNA-Seq Pre-exposure prophylaxis sample 33, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 28;medical.history: depression;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 691;viral load: not detected;prescription drugs: Truvada, Remeron;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2019;recreational drugs: speed;cigarette smoker: no;bal sampling date: 2019/10/31;mtb challenged: no;rin: 9.7;average library size: 325;sequencing run: centre2_batch2;lane: L5 Pre-exposure prophylaxis sample 33, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP33.MTB.0_RNA_R1_quant.sf
GSM5048603 RNA-Seq Pre-exposure prophylaxis sample 33, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 28;medical.history: depression;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 691;viral load: not detected;prescription drugs: Truvada, Remeron;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2019;recreational drugs: speed;cigarette smoker: no;bal sampling date: 2019/10/31;mtb challenged: yes;rin: 9.6;average library size: 326;sequencing run: centre2_batch2;lane: L5 Pre-exposure prophylaxis sample 33, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP33.MTB.1_RNA_R1_quant.sf
GSM5048604 RNA-Seq Pre-exposure prophylaxis sample 34, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Asian;Sex: M;age: 42;medical.history: None;sexually transmitted infections: Chlamydia 2017;quantiferon tb reagent: no;cd4 count: 208;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: no;cigarette smoker: no;bal sampling date: 2019/10/31;mtb challenged: no;rin: 10;average library size: 324;sequencing run: centre2_batch2;lane: L5 Pre-exposure prophylaxis sample 34, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP34.MTB.0_RNA_R1_quant.sf
GSM5048605 RNA-Seq Pre-exposure prophylaxis sample 34, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Asian;Sex: M;age: 42;medical.history: None;sexually transmitted infections: Chlamydia 2017;quantiferon tb reagent: no;cd4 count: 208;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: no;cigarette smoker: no;bal sampling date: 2019/10/31;mtb challenged: yes;rin: 9.8;average library size: 329;sequencing run: centre2_batch2;lane: L5 Pre-exposure prophylaxis sample 34, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP34.MTB.1_RNA_R1_quant.sf
GSM5048606 RNA-Seq Pre-exposure prophylaxis sample 35, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 25;medical.history: None;sexually transmitted infections: Chlamydia 2018;quantiferon tb reagent: no;cd4 count: 832;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2018;recreational drugs: cocaine;cigarette smoker: yes;bal sampling date: 2019/11/06;mtb challenged: no;rin: 9.9;average library size: 329;sequencing run: centre2_batch2;lane: L5 Pre-exposure prophylaxis sample 35, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP35.MTB.0_RNA_R1_quant.sf
GSM5048607 RNA-Seq Pre-exposure prophylaxis sample 35, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 25;medical.history: None;sexually transmitted infections: Chlamydia 2018;quantiferon tb reagent: no;cd4 count: 832;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2018;recreational drugs: cocaine;cigarette smoker: yes;bal sampling date: 2019/11/06;mtb challenged: yes;rin: 9.7;average library size: 323;sequencing run: centre2_batch2;lane: L5 Pre-exposure prophylaxis sample 35, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP35.MTB.1_RNA_R1_quant.sf
GSM5048608 RNA-Seq Pre-exposure prophylaxis sample 36, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 28;medical.history: None;sexually transmitted infections: gonorrhea PCR+;quantiferon tb reagent: no;cd4 count: 1009;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: ketamine;cigarette smoker: yes;bal sampling date: 2019/11/06;mtb challenged: no;rin: 9.5;average library size: 321;sequencing run: centre2_batch2;lane: L6 Pre-exposure prophylaxis sample 36, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP36.MTB.0_RNA_R1_quant.sf
GSM5048618 RNA-Seq Person living with HIV sample 8, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 46;medical.history: HIV (2002);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 533;viral load: not detected;prescription drugs: Complera;active ingredient: Emtricitabine, Tenofovir_DF, Rilpivirine;art start year: 2013;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/09/06;mtb challenged: no;rin: 9.1;average library size: 322;sequencing run: centre1_batch1;lane: L8 Person living with HIV sample 8, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV8.MTB.0_RNA_R1_quant.sf
GSM5048619 RNA-Seq Person living with HIV sample 8, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 46;medical.history: HIV (2002);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 533;viral load: not detected;prescription drugs: Complera;active ingredient: Emtricitabine, Tenofovir_DF, Rilpivirine;art start year: 2013;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/09/06;mtb challenged: yes;rin: 2;average library size: 328;sequencing run: centre1_batch1;lane: L8 Person living with HIV sample 8, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV8.MTB.1_RNA_R1_quant.sf
GSM5048609 RNA-Seq Pre-exposure prophylaxis sample 36, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 28;medical.history: None;sexually transmitted infections: gonorrhea PCR+;quantiferon tb reagent: no;cd4 count: 1009;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2016;recreational drugs: ketamine;cigarette smoker: yes;bal sampling date: 2019/11/06;mtb challenged: yes;rin: 9.7;average library size: 317;sequencing run: centre2_batch2;lane: L6 Pre-exposure prophylaxis sample 36, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP36.MTB.1_RNA_R1_quant.sf
GSM5048620 RNA-Seq Person living with HIV sample 9, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 56;medical.history: HIV (2002);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 536;viral load: not detected;prescription drugs: Truvada, Isentress;active ingredient: Emtricitabine, Tenofovir_DF, Raltegravir;art start year: 2004;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2017/10/11;mtb challenged: no;rin: 8.9;average library size: 315;sequencing run: centre1_batch2;lane: L3 Person living with HIV sample 9, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV9.MTB.0_RNA_R1_quant.sf
GSM5048610 RNA-Seq Pre-exposure prophylaxis sample 37, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 40;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1454;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2017;recreational drugs: cannabis;cigarette smoker: no;bal sampling date: 2019/11/27;mtb challenged: no;rin: 9.5;average library size: 315;sequencing run: centre2_batch2;lane: L6 Pre-exposure prophylaxis sample 37, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PrEP.AMP37.MTB.0_RNA_R1_quant.sf
GSM5048621 RNA-Seq Person living with HIV sample 9, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 56;medical.history: HIV (2002);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 536;viral load: not detected;prescription drugs: Truvada, Isentress;active ingredient: Emtricitabine, Tenofovir_DF, Raltegravir;art start year: 2004;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2017/10/11;mtb challenged: yes;rin: 8.8;average library size: 320;sequencing run: centre1_batch2;lane: L3 Person living with HIV sample 9, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV9.MTB.1_RNA_R1_quant.sf
GSM5048622 RNA-Seq Person living with HIV sample 10, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 60;medical.history: HIV (1992);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 269;viral load: not detected;prescription drugs: Intelence, Prezista, Tivicay, Norvir;active ingredient: Etravirine, Darunavir, Dolutegravir, Ritonavir;art start year: 1996;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/11/01;mtb challenged: no;rin: 9.2;average library size: 322;sequencing run: centre1_batch1;lane: L8 Person living with HIV sample 10, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV10.MTB.0_RNA_R1_quant.sf
GSM5048611 RNA-Seq Pre-exposure prophylaxis sample 37, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 40;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1454;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2017;recreational drugs: cannabis;cigarette smoker: no;bal sampling date: 2019/11/27;mtb challenged: yes;rin: 9.6;average library size: 320;sequencing run: centre2_batch2;lane: L6 Pre-exposure prophylaxis sample 37, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PrEP.AMP37.MTB.1_RNA_R1_quant.sf
GSM5048623 RNA-Seq Person living with HIV sample 10, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 60;medical.history: HIV (1992);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 269;viral load: not detected;prescription drugs: Intelence, Prezista, Tivicay, Norvir;active ingredient: Etravirine, Darunavir, Dolutegravir, Ritonavir;art start year: 1996;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/11/01;mtb challenged: yes;rin: 9.5;average library size: 310;sequencing run: centre1_batch1;lane: L8 Person living with HIV sample 10, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV10.MTB.1_RNA_R1_quant.sf
GSM5048612 RNA-Seq Person living with HIV sample 3, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 52;medical.history: HIV (1996);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 382;viral load: not detected;prescription drugs: Truvada, Isentress;active ingredient: Emtricitabine, Tenofovir_DF, Raltegravir;art start year: 1998;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/05/31;mtb challenged: no;rin: 9.1;average library size: 330;sequencing run: centre1_batch1;lane: L8 Person living with HIV sample 3, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV3.MTB.0_RNA_R1_quant.sf
GSM5048624 RNA-Seq Person living with HIV sample 11, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 50;medical.history: HIV (1997);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 439;viral load: not detected;prescription drugs: Complera;active ingredient: Emtricitabine, Tenofovir_DF, Rilpivirine;art start year: 1999;recreational drugs: no;cigarette smoker: yes;bal sampling date: 2017/11/29;mtb challenged: no;rin: 6.8;average library size: 357;sequencing run: centre1_batch2;lane: L3 Person living with HIV sample 11, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV11.MTB.0_RNA_R1_quant.sf
GSM5048613 RNA-Seq Person living with HIV sample 3, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 52;medical.history: HIV (1996);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 382;viral load: not detected;prescription drugs: Truvada, Isentress;active ingredient: Emtricitabine, Tenofovir_DF, Raltegravir;art start year: 1998;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/05/31;mtb challenged: yes;rin: 8.3;average library size: 261;sequencing run: centre1_batch1;lane: L8 Person living with HIV sample 3, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV3.MTB.1_RNA_R1_quant.sf
GSM5048625 RNA-Seq Person living with HIV sample 11, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 50;medical.history: HIV (1997);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 439;viral load: not detected;prescription drugs: Complera;active ingredient: Emtricitabine, Tenofovir_DF, Rilpivirine;art start year: 1999;recreational drugs: no;cigarette smoker: yes;bal sampling date: 2017/11/29;mtb challenged: yes;rin: 8.5;average library size: 356;sequencing run: centre1_batch2;lane: L3 Person living with HIV sample 11, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV11.MTB.1_RNA_R1_quant.sf
GSM5048626 RNA-Seq Person living with HIV sample 13, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: F;age: 54;medical.history: HIV (1994);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 716;viral load: not detected;prescription drugs: Complera, Reyataz, Isentress;active ingredient: Emtricitabine, Tenofovir_DF, Rilpivirine, Atazanavir, Raltegravir;art start year: 1994;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2017/12/06;mtb challenged: no;rin: 10;average library size: 352;sequencing run: centre1_batch2;lane: L1 Person living with HIV sample 13, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV13.MTB.0_RNA_R1_quant.sf
GSM5048614 RNA-Seq Person living with HIV sample 4, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 56;medical.history: HIV (2002);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1172;viral load: not detected;prescription drugs: Biktarvy;active ingredient: Emtricitabine, Tenofovir_AF, Bictegravir;art start year: 2002;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2019/12/04;mtb challenged: no;rin: 10;average library size: 321;sequencing run: centre2_batch2;lane: L6 Person living with HIV sample 4, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV4.MTB.0_RNA_R1_quant.sf
GSM5048627 RNA-Seq Person living with HIV sample 13, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: F;age: 54;medical.history: HIV (1994);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 716;viral load: not detected;prescription drugs: Complera, Reyataz, Isentress;active ingredient: Emtricitabine, Tenofovir_DF, Rilpivirine, Atazanavir, Raltegravir;art start year: 1994;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2017/12/06;mtb challenged: yes;rin: 10;average library size: 372;sequencing run: centre1_batch2;lane: L1 Person living with HIV sample 13, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV13.MTB.1_RNA_R1_quant.sf
GSM5048628 RNA-Seq Person living with HIV sample 14, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 57;medical.history: HIV (1996);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 983;viral load: not detected;prescription drugs: Kivexa, Reyataz, Norvir;active ingredient: Abacavir, Lamivudine, Atazanavir, Ritonavir;art start year: 1997;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2017/12/06;mtb challenged: no;rin: 10;average library size: 358;sequencing run: centre1_batch2;lane: L1 Person living with HIV sample 14, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV14.MTB.0_RNA_R1_quant.sf
GSM5048629 RNA-Seq Person living with HIV sample 14, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 57;medical.history: HIV (1996);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 983;viral load: not detected;prescription drugs: Kivexa, Reyataz, Norvir;active ingredient: Abacavir, Lamivudine, Atazanavir, Ritonavir;art start year: 1997;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2017/12/06;mtb challenged: yes;rin: 10;average library size: 336;sequencing run: centre1_batch2;lane: L1 Person living with HIV sample 14, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV14.MTB.1_RNA_R1_quant.sf
GSM5048615 RNA-Seq Person living with HIV sample 4, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 56;medical.history: HIV (2002);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1172;viral load: not detected;prescription drugs: Biktarvy;active ingredient: Emtricitabine, Tenofovir_AF, Bictegravir;art start year: 2002;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2019/12/04;mtb challenged: yes;rin: 9.9;average library size: 316;sequencing run: centre2_batch2;lane: L6 Person living with HIV sample 4, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV4.MTB.1_RNA_R1_quant.sf
GSM5048630 RNA-Seq Person living with HIV sample 15, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 51;medical.history: HIV x 2003;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 468;viral load: not detected;prescription drugs: Triumeq;active ingredient: Abacavir, Dolutegravir, Lamivudine;art start year: 2004;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/01/24;mtb challenged: no;rin: 9.8;average library size: 326;sequencing run: centre1_batch2;lane: L4 Person living with HIV sample 15, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV15.MTB.0_RNA_R1_quant.sf
GSM5048631 RNA-Seq Person living with HIV sample 15, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 51;medical.history: HIV x 2003;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 468;viral load: not detected;prescription drugs: Triumeq;active ingredient: Abacavir, Dolutegravir, Lamivudine;art start year: 2004;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/01/24;mtb challenged: yes;rin: 9.9;average library size: 334;sequencing run: centre1_batch2;lane: L4 Person living with HIV sample 15, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV15.MTB.1_RNA_R1_quant.sf
GSM5048616 RNA-Seq Person living with HIV sample 5, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 59;medical.history: HIV (1995);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 606;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2009;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/06/21;mtb challenged: no;rin: 9.4;average library size: 327;sequencing run: centre1_batch1;lane: L8 Person living with HIV sample 5, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV5.MTB.0_RNA_R1_quant.sf
GSM5048632 RNA-Seq Person living with HIV sample 16, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 56;medical.history: HIV (1987);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1005;viral load: not detected;prescription drugs: Genvoya;active ingredient: Emtricitabine, Tenofovir_AF, Cobicistat, Elvitegravir;art start year: 2002;recreational drugs: no;cigarette smoker: yes;bal sampling date: 2018/02/07;mtb challenged: no;rin: 8.9;average library size: 337;sequencing run: centre1_batch2;lane: L3 Person living with HIV sample 16, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV16.MTB.0_RNA_R1_quant.sf
GSM5048633 RNA-Seq Person living with HIV sample 16, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 56;medical.history: HIV (1987);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1005;viral load: not detected;prescription drugs: Genvoya;active ingredient: Emtricitabine, Tenofovir_AF, Cobicistat, Elvitegravir;art start year: 2002;recreational drugs: no;cigarette smoker: yes;bal sampling date: 2018/02/07;mtb challenged: yes;rin: 9;average library size: 326;sequencing run: centre1_batch2;lane: L3 Person living with HIV sample 16, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV16.MTB.1_RNA_R1_quant.sf
GSM5048617 RNA-Seq Person living with HIV sample 5, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 59;medical.history: HIV (1995);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 606;viral load: not detected;prescription drugs: Truvada;active ingredient: Emtricitabine, Tenofovir_DF;art start year: 2009;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/06/21;mtb challenged: yes;rin: 9.7;average library size: 262;sequencing run: centre1_batch1;lane: L8 Person living with HIV sample 5, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV5.MTB.1_RNA_R1_quant.sf
GSM5048634 RNA-Seq Person living with HIV sample 17, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 41;medical.history: HIV (2014);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1267;viral load: not detected;prescription drugs: Viread, Tivicay, Edurant;active ingredient: Tenofovir_DF, Dolutegravir, Rilpivirine;art start year: 2015;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/02/07;mtb challenged: no;rin: 8.9;average library size: 315;sequencing run: centre2_batch2;lane: L5 Person living with HIV sample 17, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV17.MTB.0_RNA_R1_quant.sf
GSM5048635 RNA-Seq Person living with HIV sample 17, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 41;medical.history: HIV (2014);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1267;viral load: not detected;prescription drugs: Viread, Tivicay, Edurant;active ingredient: Tenofovir_DF, Dolutegravir, Rilpivirine;art start year: 2015;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/02/07;mtb challenged: yes;rin: 9;average library size: 307;sequencing run: centre2_batch2;lane: L5 Person living with HIV sample 17, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV17.MTB.1_RNA_R1_quant.sf
GSM5048636 RNA-Seq Person living with HIV sample 18, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 40;medical.history: HIV (2016);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 989;viral load: not detected;prescription drugs: Viread, Tivicay, 3TC;active ingredient: Tenofovir_DF, Dolutegravir, Lamivudine;art start year: 2016;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/02/14;mtb challenged: no;rin: 9.3;average library size: 331;sequencing run: centre1_batch2;lane: L3 Person living with HIV sample 18, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV18.MTB.0_RNA_R1_quant.sf
GSM5048637 RNA-Seq Person living with HIV sample 18, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 40;medical.history: HIV (2016);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 989;viral load: not detected;prescription drugs: Viread, Tivicay, 3TC;active ingredient: Tenofovir_DF, Dolutegravir, Lamivudine;art start year: 2016;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/02/14;mtb challenged: yes;rin: 9.1;average library size: 330;sequencing run: centre1_batch2;lane: L3 Person living with HIV sample 18, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV18.MTB.1_RNA_R1_quant.sf
GSM5048638 RNA-Seq Person living with HIV sample 19, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 57;medical.history: HIV (2005);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 565;viral load: not detected;prescription drugs: Triumeq;active ingredient: Abacavir, Dolutegravir, Lamivudine;art start year: 2006;recreational drugs: cannabis;cigarette smoker: no;bal sampling date: 2018/02/14;mtb challenged: no;rin: 9.4;average library size: 324;sequencing run: centre1_batch2;lane: L5 Person living with HIV sample 19, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV19.MTB.0_RNA_R1_quant.sf
GSM5048639 RNA-Seq Person living with HIV sample 19, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 57;medical.history: HIV (2005);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 565;viral load: not detected;prescription drugs: Triumeq;active ingredient: Abacavir, Dolutegravir, Lamivudine;art start year: 2006;recreational drugs: cannabis;cigarette smoker: no;bal sampling date: 2018/02/14;mtb challenged: yes;rin: 9.6;average library size: 318;sequencing run: centre1_batch2;lane: L5 Person living with HIV sample 19, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV19.MTB.1_RNA_R1_quant.sf
GSM5048640 RNA-Seq Person living with HIV sample 20, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 58;medical.history: HIV (1997);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 727;viral load: not detected;prescription drugs: Truvada, Tybost, Prezista;active ingredient: Emtricitabine, Tenofovir_DF, Cobiscistat, Darunavir;art start year: 1997;recreational drugs: cannabis;cigarette smoker: no;bal sampling date: 2018/05/30;mtb challenged: no;rin: 8.7;average library size: 325;sequencing run: centre1_batch3;lane: L1 Person living with HIV sample 20, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV20.MTB.0_RNA_R1_quant.sf
GSM5048641 RNA-Seq Person living with HIV sample 20, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 58;medical.history: HIV (1997);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 727;viral load: not detected;prescription drugs: Truvada, Tybost, Prezista;active ingredient: Emtricitabine, Tenofovir_DF, Cobiscistat, Darunavir;art start year: 1997;recreational drugs: cannabis;cigarette smoker: no;bal sampling date: 2018/05/30;mtb challenged: yes;rin: 8.9;average library size: 317;sequencing run: centre1_batch3;lane: L1 Person living with HIV sample 20, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV20.MTB.1_RNA_R1_quant.sf
GSM5048642 RNA-Seq Person living with HIV sample 21, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 62;medical.history: HIV (2012);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 650;viral load: not detected;prescription drugs: Truvada, Tivicay;active ingredient: Emtricitabine, Tenofovir_DF, Dolutegravir;art start year: 2012;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/06/20;mtb challenged: no;rin: 8.9;average library size: 318;sequencing run: centre2_batch1;lane: L3 Person living with HIV sample 21, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV21.MTB.0_RNA_R1_quant.sf
GSM5048643 RNA-Seq Person living with HIV sample 21, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 62;medical.history: HIV (2012);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 650;viral load: not detected;prescription drugs: Truvada, Tivicay;active ingredient: Emtricitabine, Tenofovir_DF, Dolutegravir;art start year: 2012;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/06/20;mtb challenged: yes;rin: 8.8;average library size: 317;sequencing run: centre2_batch1;lane: L3 Person living with HIV sample 21, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV21.MTB.1_RNA_R1_quant.sf
GSM5048644 RNA-Seq Person living with HIV sample 23, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 33;medical.history: HIV (2017);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 633;viral load: not detected;prescription drugs: Genvoya;active ingredient: Emtricitabine, Tenofovir_AF, Cobicistat, Elvitegravir;art start year: 2017;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/07/11;mtb challenged: no;rin: 9;average library size: 316;sequencing run: centre2_batch1;lane: L4 Person living with HIV sample 23, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV23.MTB.0_RNA_R1_quant.sf
GSM5048645 RNA-Seq Person living with HIV sample 23, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 33;medical.history: HIV (2017);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 633;viral load: not detected;prescription drugs: Genvoya;active ingredient: Emtricitabine, Tenofovir_AF, Cobicistat, Elvitegravir;art start year: 2017;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2018/07/11;mtb challenged: yes;rin: 9;average library size: 321;sequencing run: centre2_batch1;lane: L4 Person living with HIV sample 23, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV23.MTB.1_RNA_R1_quant.sf
GSM5048646 RNA-Seq Person living with HIV sample 25, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 60;medical.history: HIV (2006);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 906;viral load: not detected;prescription drugs: Atripla;active ingredient: Emtricitabine, Tenofovir_DF, Efavirenz;art start year: 2007;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/07/04;mtb challenged: no;rin: 8.2;average library size: 309;sequencing run: centre2_batch1;lane: L4 Person living with HIV sample 25, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV25.MTB.0_RNA_R1_quant.sf
GSM5048647 RNA-Seq Person living with HIV sample 25, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 60;medical.history: HIV (2006);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 906;viral load: not detected;prescription drugs: Atripla;active ingredient: Emtricitabine, Tenofovir_DF, Efavirenz;art start year: 2007;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/07/04;mtb challenged: yes;rin: 8.8;average library size: 315;sequencing run: centre2_batch1;lane: L4 Person living with HIV sample 25, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV25.MTB.1_RNA_R1_quant.sf
GSM5048648 RNA-Seq Person living with HIV sample 26, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 50;medical.history: HIV (2000);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 471;viral load: not detected;prescription drugs: Atripla;active ingredient: Emtricitabine, Tenofovir_DF, Efavirenz;art start year: 2010;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/07/04;mtb challenged: no;rin: 8.9;average library size: 314;sequencing run: centre2_batch1;lane: L4 Person living with HIV sample 26, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV26.MTB.0_RNA_R1_quant.sf
GSM5048649 RNA-Seq Person living with HIV sample 26, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 50;medical.history: HIV (2000);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 471;viral load: not detected;prescription drugs: Atripla;active ingredient: Emtricitabine, Tenofovir_DF, Efavirenz;art start year: 2010;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/07/04;mtb challenged: yes;rin: 9.3;average library size: 314;sequencing run: centre2_batch1;lane: L4 Person living with HIV sample 26, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV26.MTB.1_RNA_R1_quant.sf
GSM5048650 RNA-Seq Person living with HIV sample 27, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 59;medical.history: HIV (2017);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 501;viral load: not detected;prescription drugs: Descovy, Isentress;active ingredient: Emtricitabine, Tenofovir_AF, Raltegravir;art start year: 2017;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/09/19;mtb challenged: no;rin: 9.6;average library size: 330;sequencing run: centre1_batch3;lane: L2 Person living with HIV sample 27, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;PLWH.AMV27.MTB.0_RNA_R1_quant.sf
GSM5048651 RNA-Seq Person living with HIV sample 27, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 59;medical.history: HIV (2017);sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 501;viral load: not detected;prescription drugs: Descovy, Isentress;active ingredient: Emtricitabine, Tenofovir_AF, Raltegravir;art start year: 2017;recreational drugs: no;cigarette smoker: no;bal sampling date: 2018/09/19;mtb challenged: yes;rin: 9.4;average library size: 327;sequencing run: centre1_batch3;lane: L2 Person living with HIV sample 27, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;PLWH.AMV27.MTB.1_RNA_R1_quant.sf
GSM5048552 RNA-Seq Healthy control sample 2, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 59;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 495;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2017/02/01;mtb challenged: no;rin: 9.6;average library size: 261;sequencing run: centre1_batch1;lane: L7 Healthy control sample 2, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC2.MTB.0_RNA_R1_quant.sf
GSM5048553 RNA-Seq Healthy control sample 2, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 59;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 495;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2017/02/01;mtb challenged: yes;rin: 9.3;average library size: 325;sequencing run: centre1_batch1;lane: L7 Healthy control sample 2, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC2.MTB.1_RNA_R1_quant.sf
GSM5048554 RNA-Seq Healthy control sample 7, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 49;medical.history: hypertension, diabetes, gout;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 500;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/05/03;mtb challenged: no;rin: 9;average library size: 334;sequencing run: centre1_batch1;lane: L7 Healthy control sample 7, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC7.MTB.0_RNA_R1_quant.sf
GSM5048555 RNA-Seq Healthy control sample 7, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 49;medical.history: hypertension, diabetes, gout;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 500;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/05/03;mtb challenged: yes;rin: 9.6;average library size: 346;sequencing run: centre1_batch1;lane: L7 Healthy control sample 7, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC7.MTB.1_RNA_R1_quant.sf
GSM5048556 RNA-Seq Healthy control sample 8, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 25;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1536;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/11/22;mtb challenged: no;rin: 8.4;average library size: 362;sequencing run: centre1_batch2;lane: L2 Healthy control sample 8, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC8.MTB.0_RNA_R1_quant.sf
GSM5048557 RNA-Seq Healthy control sample 8, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 25;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1536;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/11/22;mtb challenged: yes;rin: 8.3;average library size: 369;sequencing run: centre1_batch2;lane: L2 Healthy control sample 8, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC8.MTB.1_RNA_R1_quant.sf
GSM5048558 RNA-Seq Healthy control sample 9, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 58;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1173;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2019/12/04;mtb challenged: no;rin: 10;average library size: 322;sequencing run: centre2_batch2;lane: L6 Healthy control sample 9, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC9.MTB.0_RNA_R1_quant.sf
GSM5048559 RNA-Seq Healthy control sample 9, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 58;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1173;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: cannabis;cigarette smoker: yes;bal sampling date: 2019/12/04;mtb challenged: yes;rin: 10;average library size: 317;sequencing run: centre2_batch2;lane: L6 Healthy control sample 9, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC9.MTB.1_RNA_R1_quant.sf
GSM5048560 RNA-Seq Healthy control sample 10, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library ethnicity: Caucasian;Sex: M;age: 29;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1091;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/01/11;mtb challenged: no;rin: 9;average library size: 321;sequencing run: centre2_batch1;lane: L3 Healthy control sample 10, Alveolar macrophage, Mycobacterium tuberculosis non-challenged library;mRNA, poly-A selected;HC.AMC10.MTB.0_RNA_R1_quant.sf
GSM5048561 RNA-Seq Healthy control sample 10, Alveolar macrophage, Mycobacterium tuberculosis challenged library ethnicity: Caucasian;Sex: M;age: 29;medical.history: None;sexually transmitted infections: no;quantiferon tb reagent: no;cd4 count: 1091;viral load: not tested;prescription drugs: none;active ingredient: none;art start year: none;recreational drugs: no;cigarette smoker: no;bal sampling date: 2017/01/11;mtb challenged: yes;rin: 9;average library size: 323;sequencing run: centre2_batch1;lane: L3 Healthy control sample 10, Alveolar macrophage, Mycobacterium tuberculosis challenged library;mRNA, poly-A selected;HC.AMC10.MTB.1_RNA_R1_quant.sf
Platform GPL20301  : Illumina HiSeq 4000 (Homo sapiens)
Literature 34473646  
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xCell Plot
* p<0.05 ** p<0.01