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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19 Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	39905220	N82L	ORF3a	ORF3a	Cell line		View
2	39905220	N82W	ORF3a	ORF3a	Cell line		View
3	33205709	Q57H	ORF3a	ORF3a	Cell line		View
4	39048693	T9I	ORF3a	ORF3a	Cell line	R L	View
5	39048693	C25418T	ORF3a	ORF3a	Cell line	R L	View
6	35164548	Q57H	ORF3a	ORF3a	Cell line	G R L	View
7	37796123	T9I	ORF3a	ORF3a	COVID-19 Cell line	G R	View
8	36537060	C25584T	ORF3a	ORF3a		G	View
9	35632430	H78K	ORF3a	ORF3a		G L	View
10	35632430	L140F	ORF3a	ORF3a		G L	View
11	35551247	Q57H	ORF3a	ORF3a		G L	View
12	35710544	Q57H	ORF3a	ORF3a		G R L	View
13	36512569	A25596T	ORF3a	ORF3a		G R L	View
14	36512569	G25437T	ORF3a	ORF3a		G R L	View
15	36512569	R68S	ORF3a	ORF3a		G R L	View
16	36512569	L15F	ORF3a	ORF3a		G R L	View
17	35632749	T223I	ORF3a	ORF3a		G R L	View
18	35632749	V50A	ORF3a	ORF3a		G R L	View
19	35538074	V255X	ORF3a	ORF3a		R I C	View
20	35624123	L219V	ORF3a	ORF3a		R	View
21	35706980	L108F	ORF3a	ORF3a		S C L	View
22	35726918	Q57H	ORF3a	ORF3a		R S L	View
23	35764775	Q57H	ORF3a	ORF3a		L	View
24	35764775	T151I	ORF3a	ORF3a		L	View
25	36852417	G49V	ORF3a	ORF3a			View
26	37965255	T223I	ORF3a	ORF3a	COVID-19	G R C L	View
27	38763300	T223I	ORF3a	ORF3a	COVID-19	G R S L	View
28	38601946	C25810T	ORF3a	ORF3a	COVID-19	G R C L	View
29	38601946	L140F	ORF3a	ORF3a	COVID-19	G R C L	View
30	37275159	C222T	ORF3a	ORF3a	COVID-19	G R S C L	View
31	37275159	S74S	ORF3a	ORF3a	COVID-19	G R S C L	View
32	37275159	T223I	ORF3a	ORF3a	COVID-19	G R S C L	View
33	37275159	T64T	ORF3a	ORF3a	COVID-19	G R S C L	View
34	33900193	Q57H	ORF3a	ORF3a	COVID-19	G S L	View
35	39459859	G174C	ORF3a	ORF3a	COVID-19	G R L	View
36	36846745	P240L	ORF3a	ORF3a	COVID-19	G R S C L	View
37	35966675	S26L	ORF3a	ORF3a	COVID-19	G R S C L	View
38	36687433	S26L	ORF3a	ORF3a	COVID-19	G R S L	View
39	37243279	L275F	ORF3a	ORF3a	COVID-19	G R S C L	View
40	37243279	S216L	ORF3a	ORF3a	COVID-19	G R S C L	View
41	37243279	T229N	ORF3a	ORF3a	COVID-19	G R S C L	View
42	36687433	Q57H	ORF3a	ORF3a	COVID-19	G R S L	View
43	36310647	V202L	ORF3a	ORF3a	COVID-19	G R S	View
44	36310647	A23V	ORF3a	ORF3a	COVID-19	G R S	View
45	37744926	C25466T	ORF3a	ORF3a	COVID-19	G R S C L	View
46	37376693	H78Y	ORF3a	ORF3a	COVID-19	G R S L	View
47	37224159	T64T	ORF3a;NSP3	ORF3a;ORF1a	COVID-19	G R L	View
48	37224159	C25416T	ORF3a	ORF3a	COVID-19	G R L	View
49	37224159	C26060T	ORF3a	ORF3a	COVID-19	G R L	View
50	37224159	T2231I	ORF3a	ORF3a	COVID-19	G R L	View
51	37224159	T223I	ORF3a	ORF3a	COVID-19	G R L	View
52	36755883	T223I	ORF3a	ORF3a	COVID-19	G R L	View
53	37376693	C25672T	ORF3a	ORF3a	COVID-19	G R S L	View
54	37376693	L94F	ORF3a	ORF3a	COVID-19	G R S L	View
55	37376693	C25961T	ORF3a	ORF3a	COVID-19	G R S L	View
56	37376693	T190I	ORF3a	ORF3a	COVID-19	G R S L	View
57	37376693	G26167T	ORF3a	ORF3a	COVID-19	G R S L	View
58	37376693	V259L	ORF3a	ORF3a	COVID-19	G R S L	View
59	34634791	S171L	ORF3a	ORF3a	COVID-19	G R S	View
60	34634791	S26L	ORF3a	ORF3a	COVID-19	G R S	View
61	36687433	A99S	ORF3a	ORF3a	COVID-19	G R S L	View
62	34634791	Q57H	ORF3a	ORF3a	COVID-19	G R S	View
63	34634791	S92L	ORF3a	ORF3a	COVID-19	G R S	View
64	36687433	S171L	ORF3a	ORF3a	COVID-19	G R S L	View
65	37573409	C25904T	ORF3a	ORF3a	COVID-19	G R S C L	View
66	37573409	G26211T	ORF3a	ORF3a	COVID-19	G R S C L	View
67	37692895	A23V	ORF3a	ORF3a	COVID-19	G R C	View
68	34424256	L15F	ORF3a	ORF3a	COVID-19	G S L	View
69	37124420	T32I	ORF3a	ORF3a	COVID-19	G S I C L	View
70	36778569	G49V	ORF3a	ORF3a	COVID-19	G R S L	View
71	37243279	R126S	ORF3a	ORF3a	COVID-19	G R S C L	View
72	35060147	A33S	ORF3a	ORF3a	COVID-19	G L	View
73	35229308	T14I	ORF3a	ORF3a	COVID-19	G R L	View
74	39604601	A54S	ORF3a	ORF3a	COVID-19	G L	View
75	39604601	D173G	ORF3a	ORF3a	COVID-19	G L	View
76	32474553	G251V	ORF3a	ORF3a	COVID-19	G R	View
77	33920487	Q57H	ORF3a	ORF3a	COVID-19	G R	View
78	34547443	Q57H	ORF3a	ORF3a	COVID-19	G R L	View
79	39339912	Q213K	ORF3a	ORF3a	COVID-19	G R	View
80	34547443	G196V	ORF3a	ORF3a	COVID-19	G R	View
81	38125422	G26144T	ORF3a	ORF3a	COVID-19	G R S C L	View
82	38125422	G251V	ORF3a	ORF3a	COVID-19	G R S C L	View
83	34547443	G251V	ORF3a	ORF3a	COVID-19	G R	View
84	32742035	Q57H	ORF3a	ORF3a	COVID-19	R	View
85	32543353	A59D	ORF3a	ORF3a	COVID-19	R S L	View
86	32543353	C176A	ORF3a	ORF3a	COVID-19	R S L	View
87	32543353	G251V	ORF3a	ORF3a	COVID-19	R S L	View
88	38605705	C25584T	ORF3a	ORF3a	COVID-19	G R S C L	View
89	38605705	C25685T	ORF3a	ORF3a	COVID-19	G R S C L	View
90	38605705	C26060T	ORF3a	ORF3a	COVID-19	G R S C L	View
91	38605705	A98V	ORF3a	ORF3a	COVID-19	G R S C L	View
92	38605705	T223I	ORF3a	ORF3a	COVID-19	G R S C L	View
93	40143342	A99V	ORF3a	ORF3a	COVID-19	R S L	View
94	40143342	P240S	ORF3a	ORF3a	COVID-19	R S L	View
95	40143342	S26L	ORF3a	ORF3a	COVID-19	R S L	View
96	40143342	W149L	ORF3a	ORF3a	COVID-19	R S L	View
97	34729465	Q213K	ORF3a	ORF3a	COVID-19	I	View
98	33966351	G25563T	ORF3a	ORF3a	COVID-19	R L	View
99	35966675	S253P	ORF3a	ORF3a	COVID-19	R S C L	View
100	36008511	H78Y	ORF3a	ORF3a	COVID-19	R C L	View
101	36008511	S171L	ORF3a	ORF3a	COVID-19	R C L	View
102	36008511	I158V	ORF3a	ORF3a	COVID-19	R C L	View
103	36090111	Q57H	ORF3a	ORF3a	COVID-19	R C L	View
104	36090111	S26L	ORF3a	ORF3a	COVID-19	R C L	View
105	36090111	W131C	ORF3a	ORF3a	COVID-19	R C L	View
106	36405589	T223I	ORF3a	ORF3a	COVID-19	R S C L	View
107	36560780	Q57H	ORF3a	ORF3a	COVID-19		View
108	36841805	S26L	ORF3a	ORF3a	COVID-19	R	View
109	35614572	Q57H	ORF3a	ORF3a	COVID-19	R	View
110	35707000	G25563T	ORF3a	ORF3a	COVID-19	R	View
111	35707000	Q57H	ORF3a	ORF3a	COVID-19	R	View
112	35759503	A25439C	ORF3a	ORF3a	COVID-19	R L	View
113	35759503	C25469T	ORF3a	ORF3a	COVID-19	R L	View
114	35759503	F43C	ORF3a	ORF3a	COVID-19	R L	View
115	35759503	G25947C	ORF3a	ORF3a	COVID-19	R L	View
116	35759503	G25996T	ORF3a	ORF3a	COVID-19	R L	View
117	35759503	K16T	ORF3a	ORF3a	COVID-19	R L	View
118	35759503	Q185H	ORF3a	ORF3a	COVID-19	R L	View
119	35759503	S26L	ORF3a	ORF3a	COVID-19	R L	View
120	35759503	T25520G	ORF3a	ORF3a	COVID-19	R L	View
121	35905853	G172V	ORF3a	ORF3a	COVID-19	R L	View
122	35905853	Q57H	ORF3a	ORF3a	COVID-19	R L	View
123	33049387	G251V	ORF3a	ORF3a	COVID-19		View
124	33384909	G224C	ORF3a	ORF3a	COVID-19	R	View
125	33384909	H182L	ORF3a	ORF3a	COVID-19	R	View
126	33384909	H182Y	ORF3a	ORF3a	COVID-19	R	View
127	33384909	L219V	ORF3a	ORF3a	COVID-19	R	View
128	33384909	T229I	ORF3a	ORF3a	COVID-19	R	View
129	35891618	Q57H	ORF3a	ORF3a	COVID-19	S L	View
130	37903828	P42L	ORF3a	ORF3a	COVID-19	R L	View
131	37903828	S26L	ORF3a	ORF3a	COVID-19	R L	View
132	37903828	Q57H	ORF3a	ORF3a	COVID-19	R L	View
133	37903828	S253P	ORF3a	ORF3a	COVID-19	R L	View
134	37903828	L83F	ORF3a	ORF3a	COVID-19	R	View
135	38303011	Q57H	ORF3a	ORF3a	COVID-19		View
136	38348230	S26L	ORF3a	ORF3a	COVID-19	C L	View
137	38348230	A54S	ORF3a	ORF3a	COVID-19	C L	View
138	32300673	C25810G	ORF3a	ORF3a	COVID-19	R	View
139	32300673	G26144T	ORF3a	ORF3a	COVID-19	R	View
140	32300673	G251V	ORF3a	ORF3a	COVID-19	R	View
141	32300673	L140V	ORF3a	ORF3a	COVID-19	R	View
142	37529147	T223I	ORF3a	ORF3a	COVID-19	R S L	View
143	37529147	T64T	ORF3a	ORF3a	COVID-19	R S L	View
144	39604601	V48F	ORF3a	ORF3a	COVID-19	L	View
145	39861827	C25904T	ORF3a	ORF3a	COVID-19	R L	View
146	40006937	C25469T	ORF3a	ORF3a	COVID-19	S L	View
147	40006937	S26L	ORF3a	ORF3a	COVID-19	S L	View
148	33090512	Q57H	ORF3a	ORF3a	COVID-19	R	View
149	33090512	G251V	ORF3a	ORF3a	COVID-19	R	View
150	33219681	G251V	ORF3a	ORF3a	COVID-19	R S C L	View
151	33347622	G251V	ORF3a	ORF3a	COVID-19		View
152	33350913	G251V	ORF3a	ORF3a	COVID-19	R S C L	View
153	33580783	G25563T	ORF3a	ORF3a	COVID-19	R	View
154	33815459	G25563T	ORF3a	ORF3a	COVID-19	R S L	View
155	33815459	G57H	ORF3a	ORF3a	COVID-19	R S L	View
156	34030593	G251V	ORF3a	ORF3a	COVID-19	R L	View
157	34188167	G251V	ORF3a	ORF3a	COVID-19		View
158	34578142	A26194T	ORF3a	ORF3a	COVID-19	R C L	View
159	34578142	T268S	ORF3a	ORF3a	COVID-19	R C L	View
160	34578142	C25611A	ORF3a	ORF3a	COVID-19	R C L	View
161	34733263	Q57H	ORF3a	ORF3a	COVID-19	R	View
162	35126886	D155Y	ORF3a	ORF3a	COVID-19	L	View
163	35208920	Q57H	ORF3a	ORF3a	COVID-19	R L	View
164	32793182	Q57H	ORF3a	ORF3a	COVID-19	R	View
165	32793182	G251V	ORF3a	ORF3a	COVID-19	R	View
166	32937868	G25563T	ORF3a	ORF3a	COVID-19	R L	View
167	32937868	Q57H	ORF3a	ORF3a	COVID-19	R L	View
168	33184173	G25563T	ORF3a	ORF3a	COVID-19		View
169	33184173	Q57H	ORF3a	ORF3a	COVID-19		View
170	33760807	Q57H	ORF3a	ORF3a	COVID-19	R S L	View
171	33920487	G172V	ORF3a	ORF3a	COVID-19	R	View
172	34468954	S177I	ORF3a	ORF3a	COVID-19	R C L	View
173	36343703	G25563T	ORF3a	ORF3a	COVID-19	R	View
174	36343703	Q57H	ORF3a	ORF3a	COVID-19	R	View
175	36343703	G26144T	ORF3a	ORF3a	COVID-19	R	View
176	36343703	G251V	ORF3a	ORF3a	COVID-19	R	View
177	32515358	G26144T	ORF3a	ORF3a	COVID-19	R L	View
178	32515358	G251V	ORF3a	ORF3a	COVID-19	R L	View
179	32595352	G25563T	ORF3a	ORF3a	COVID-19	R	View
180	32595352	Q57H	ORF3a	ORF3a	COVID-19	R	View
181	32595354	G25563T	ORF3a	ORF3a	COVID-19	R L	View
182	32595354	Q57H	ORF3a	ORF3a	COVID-19	R L	View
183	33149541	G251V	ORF3a	ORF3a	COVID-19	R	View
184	33662015	Q57H	ORF3a	ORF3a	COVID-19	R L	View
185	38632523	C25416T	ORF3a	ORF3a	COVID-19	G R L	View
186	38632523	C25584T	ORF3a	ORF3a	COVID-19	G R L	View
187	38632523	C26060T	ORF3a	ORF3a	COVID-19	G R L	View
188	38632523	T223I	ORF3a	ORF3a	COVID-19	G R L	View
189	40063870	N144S	ORF1ab;ORF3a	ORF1ab;ORF3a	COVID-19	R L	View
190	36016239	C25936T	ORF3a	ORF3a	COVID-19	R L	View
191	36016239	H182Y	ORF3a	ORF3a	COVID-19	R L	View
192	33357233	Q57H	ORF3a	ORF3a	COVID-19	R	View
193	35914217	L37I	ORF3a	ORF3a	COVID-19	R C	View
194	35914217	L73I	ORF3a	ORF3a	COVID-19	R C	View
195	39047088	I37V	ORF3a	ORF3a	Cell line	R S	View