HIV Target gene Detail Information

> MTRFR Gene Search Result


Gene Information
Gene Name MTRFR
Gene ID 91574
Gene Full Name mitochondrial translation release factor in rescue
Gene Alias C12orf65|COXPD7|SPG55|mtRF-R
Transcripts ENSG00000130921
Virus HIV
Gene Type protein-coding
HPA Location Info Nucleoplasm, Cytosol;Mitochondria;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q9H3J6
HGNC ID HGNC:26784
OMIM ID 613541
Summary This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Target gene [MTRFR] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000185 chr12 772 25 2 799 View
4009494 chr12 11 0 0 11 View

Target gene [MTRFR] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE30738 		Chip-seq 2 Illumina Genome Analyzer II (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE144332 RNA-seq 75 NextSeq 550 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE30738 - MTRFR peak across samples

Peak Plot

> Dataset: GSE220859 - MTRFR peak across samples

Peak Plot

> Dataset: GSE211651 - MTRFR peak across samples

Peak Plot

> Dataset: GSE221688 - MTRFR peak across samples

Peak Plot

> Dataset: GSE165705 - MTRFR peak across samples

Peak Plot

> Dataset: GSE165703 - MTRFR peak across samples

Peak Plot

> Dataset: GSE144329 - MTRFR peak across samples

Peak Plot

> Dataset: GSE100266 - MTRFR peak across samples

Peak Plot