All Curated Mutation Sites in DENV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in DENV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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Click the button below to quickly view the viral genes/regions/protein for mutation

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NS2A
  
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NS3
  
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NS5
  
prM
  

Keyword: NS3
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 28767984 V534V
NS3
NS3
Dengue
G
R
S
L
View
2 25811657 R337K
NS3
NS3
Dengue
G
R
S
C
L
View
3 25811657 I600T
NS3
NS3
Dengue
G
R
S
C
L
View
4 25811657 K170E
NS3
NS3
Dengue
G
R
S
C
L
View
5 25811657 S171N
NS3
NS3
Dengue
G
R
S
C
L
View
6 25811657 A558V
NS3
NS3
Dengue
G
R
S
C
L
View
7 24007412 K590R
NS3
NS3
Dengue
G
S
L
View
8 37112962 K107R
NS3
NS3
Dengue
G
R
S
L
View
9 37112962 A4843G
NS3
NS3
Dengue
G
R
S
L
View
10 40045383 T532V
NS3
NS3
Dengue
G
R
S
C
L
View
11 40045383 A373S
NS3
NS3
Dengue
G
R
S
C
L
View
12 40045383 C375L
NS3
NS3
Dengue
G
R
S
C
L
View
13 40045383 D371X
NS3
NS3
Dengue
G
R
S
C
L
View
14 40045383 E181D
NS3
NS3
Dengue
G
R
S
C
L
View
15 40045383 E93X
NS3
NS3
Dengue
G
R
S
C
L
View
16 40045383 F362V
NS3
NS3
Dengue
G
R
S
C
L
View
17 40045383 G369R
NS3
NS3
Dengue
G
R
S
C
L
View
18 40045383 G380R
NS3
NS3
Dengue
G
R
S
C
L
View
19 40045383 I366H
NS3
NS3
Dengue
G
R
S
C
L
View
20 40045383 I372H
NS3
NS3
Dengue
G
R
S
C
L
View
21 40045383 K367Q
NS3
NS3
Dengue
G
R
S
C
L
View
22 40045383 K381E
NS3
NS3
Dengue
G
R
S
C
L
View
23 40045383 N370K
NS3
NS3
Dengue
G
R
S
C
L
View
24 40045383 N374K
NS3
NS3
Dengue
G
R
S
C
L
View
25 40045383 N379E
NS3
NS3
Dengue
G
R
S
C
L
View
26 40045383 R377A
NS3
NS3
Dengue
G
R
S
C
L
View
27 40045383 S365Q
NS3
NS3
Dengue
G
R
S
C
L
View
28 40045383 V363C
NS3
NS3
Dengue
G
R
S
C
L
View
29 40045383 W361V
NS3
NS3
Dengue
G
R
S
C
L
View
30 27181378 N374H
NS3
NS3
Cell line
D
G
View
31 37555662 P364S
NS3
NS3
Cell line
G
S
View
32 32402284 E250V
NS3
NS3
Cell line
G
R
View
33 37555662 D180V
NS3
NS3
Cell line
G
S
View
34 37555662 R170S
NS3
NS3
Cell line
G
S
View
35 37555662 R186K
NS3
NS3
Cell line
G
S
View
36 37555662 D223N
NS3
NS3
Cell line
G
S
View
37 37555662 D371V
NS3
NS3
Cell line
G
S
View
38 37555662 D613V
NS3
NS3
Cell line
G
S
View
39 37555662 D613Y
NS3
NS3
Cell line
G
S
View
40 37555662 N189K
NS3
NS3
Cell line
G
S
View
41 37555662 Q467R
NS3
NS3
Cell line
G
S
View
42 37555662 R569L
NS3
NS3
Cell line
G
S
View
43 37555662 G92E
NS3
NS3
Cell line
G
S
View
44 37555662 K112I
NS3
NS3
Cell line
G
S
View
45 37555662 K112Q
NS3
NS3
Cell line
G
S
View
46 37555662 K112T
NS3
NS3
Cell line
G
S
View
47 37555662 E514K
NS3
NS3
Cell line
G
S
View
48 37555662 R538K
NS3
NS3
Cell line
G
S
View
49 37555662 V226M
NS3
NS3
Cell line
G
S
View
50 37378517 N1541S
NS3
NS3
Cell line
G
R
View
51 37378517 A4716G
NS3
NS3
Cell line
G
R
View
52 28456663 I351V
NS3
NS3
Cell line
G
S
View
53 28456663 Y487H
NS3
NS3
Cell line
G
S
View
54 28456663 D535E
NS3
NS3
Cell line
G
S
View
55 28456663 V567I
NS3
NS3
Cell line
G
S
View
56 28456663 R588K
NS3
NS3
Cell line
G
S
View
57 24083095 K141S
NS3
NS3

G
View
Contents
Description

The table shows all curated mutation sites of DENV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.