Gene Name	ATP23
Gene ID	91419
Gene Full Name	ATP23 metallopeptidase and ATP synthase assembly factor homolog
Gene Alias	KUB3|XRCC6BP1
Transcripts	ENSG00000166896
Virus	HIV
Gene Type	protein-coding
HPA Location Info	Vesicles, Plasma membrane;Cell Junctions, Cytosol;
Membrane Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9Y6H3
HGNC ID	HGNC:29452
OMIM ID	619760
Summary	The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011309	chr12	7	0	0	7	View

Data ID	Experiment type	Sample number	Platform
C   GSE30738	Chip-seq	2	Illumina Genome Analyzer II (Homo sapiens)
C   GSE220859	Chip-seq	11	Illumina NovaSeq 6000 (Homo sapiens)
GSE128121	RNA-seq	16	Illumina HiSeq 4000 (Homo sapiens)
GSE165708	RNA-seq	100	Illumina HiSeq 4000 (Homo sapiens)
C   GSE211651	Chip-seq;RNA-seq;PRO-seq	39	Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE162914	RNA-seq	211	Illumina HiSeq 2500 (Homo sapiens)
C   GSE221688	Chip-seq;scATAC-Seq;scRNA-Seq	12	Illumina NovaSeq 6000 (Homo sapiens)
GSE144332	RNA-seq	75	NextSeq 550 (Homo sapiens)
C   GSE100376	ATAC-seq	24	Illumina NextSeq 500 (Homo sapiens)
C   GSE165705	Chip-seq	30	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE165703	ATAC-seq	82	Illumina HiSeq 4000 (Homo sapiens)
C   GSE144329	ATAC-seq	96	NextSeq 550 (Homo sapiens)
GSE205204	RNA-seq	14	Illumina NovaSeq 6000 (Homo sapiens)
GSE167211	RNA-seq	1	Illumina HiSeq 2000 (Homo sapiens)
GSE246082	RNA-seq	6	Illumina HiSeq 4000 (Homo sapiens)
C   GSE100266	ATAC-seq;Chip-seq;RNA-seq	32	Illumina HiSeq 2500 (Homo sapiens)
GSE125686	RNA-seq	62	Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE164264	RNA-seq	6	BGISEQ-500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE30738 - ATP23 peak across samples

Peak Plot

> Dataset: GSE220859 - ATP23 peak across samples

Peak Plot

> Dataset: GSE211651 - ATP23 peak across samples

Peak Plot

> Dataset: GSE221688 - ATP23 peak across samples

Peak Plot

> Dataset: GSE100376 - ATP23 peak across samples

Peak Plot

> Dataset: GSE165705 - ATP23 peak across samples

Peak Plot

> Dataset: GSE165703 - ATP23 peak across samples

Peak Plot

> Dataset: GSE144329 - ATP23 peak across samples

Peak Plot

> Dataset: GSE100266 - ATP23 peak across samples

Peak Plot