HIV Target gene Detail Information

> LRTOMT Gene Search Result


Gene Information
Gene Name LRTOMT
Gene ID 220074
Gene Full Name leucine rich transmembrane and O-methyltransferase domain containing
Gene Alias CFAP111|DFNB63|LRRC51|LRRC51-TOMT|TOMT
Transcripts ENSG00000284922
Virus HIV
Gene Type protein-coding
HPA Location Info Microtubules;
Membrane Info Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8WZ04
HGNC ID HGNC:25033
OMIM ID 612414
Summary This locus represents naturally occurring readthrough transcription between the neighboring LRRC51 (leucine-rich repeat containing 51) and TOMT (transmembrane O-methyltransferase) genes on chromosome 11. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. Multiple reports implicate mutations in this gene in nonsyndromic deafness.[provided by RefSeq, Feb 2021]
Target gene [LRTOMT] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4010272 chr11 5 3 1 9 View

Target gene [LRTOMT] related to Omics data
Data ID Experiment type Sample number Platform
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE211651 - LRTOMT peak across samples

Peak Plot

> Dataset: GSE221688 - LRTOMT peak across samples

Peak Plot

> Dataset: GSE100266 - LRTOMT peak across samples

Peak Plot