EBV Target gene Detail Information

> ME3 Gene Search Result


Gene Information
Gene Name ME3
Gene ID 10873
Gene Full Name malic enzyme 3
Gene Alias NADP-ME
Transcripts ENSG00000151376
Virus EBV
Gene Type protein-coding
HPA Location Info
Membrane Info Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q16798
HGNC ID HGNC:6985
OMIM ID 604626
Summary Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Target gene [ME3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000105 chr11 24 124 22 170 View

Target gene [ME3] related to Omics data
Data ID Experiment type Sample number Platform
GSE42867 Expression array 12 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
C
  GSE246060 		Chip-seq 26 Illumina NovaSeq 6000 (Homo sapiens)
GSE45919 Expression array 24 Illumina HumanHT-12 V4.0 expression beadchip
GSE198332 Methylation profiling (Array) 7 Infinium MethylationEPIC
GSE223328 Expression array 16 Agilent-072363 SurePrint G3 Human GE v3 8x60K Microarray 039494 [Probe Name Version]
GSE208281 RNA-seq 50 Illumina NextSeq 500 (Homo sapiens)
GSE100458 Expression array 14 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array [CDF: Brainarray HGU133Plus2_Hs_ENTREZG_v21]
C
  GSE198334 		Chip-seq 4 Illumina NextSeq 500 (Homo sapiens)
GSE165194 RNA-seq 3 Illumina NextSeq 500 (Homo sapiens)
C
  GSE246059 		ATAC-seq 8 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE177046 RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
GSE135644 Expression array 10 Sentrix Human-6 v2 Expression BeadChip
C
  GSE225248 		Chip-seq 12 Illumina NextSeq 500 (Homo sapiens)
GSE102203 Expression array 10 [HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [probe set (exon) version]
GSE85599 Expression array 17 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE12452 Expression array 41 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
GSE58240 Expression array 32 Illumina HumanHT-12 V4.0 expression beadchip
E
  GSE181906 		RNA-seq 24 Illumina NovaSeq 6000 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE181906 - ME3 expression across samples

Volcano Plot

Bar Plot