Virus Dataset Detail

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Dataset Information
Accession GSE12452
Status 2008/8/16
Title mRNA expression profiling of nasopharyngeal carcinoma
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Nasopharyngeal carcinoma is an Epstein-Barr virus-associated epithelial cancer with high prevalence in Southeast Asia. mRNA expression levels were measured for essentially all human genes and all latent Epstein-Barr virus (EBV) genes in nasopharyngeal carcinoma tissue samples and normal nasopharyngeal tissues. Data were analyzed for differential gene expression between tumor and normal tissue and for correlations with levels of viral gene expression. Primary publications: Sengupta et al, 2006, Cancer Research 66(16): 7999-8006. Dodd et al, 2006, Cancer Epidemiology, Biomarkers & Prevention 15(11): 2216-2225. In subsequent studies using the same set of tissue samples, microRNA levels were measured in tumors and normal tissues and analyzed for correlations with differential target gene expression (Sengupta et al, 2008, Proc. Nat. Acad. Sci. USA 105: 5874-5878.) Keywords: mRNA expression profiling
Samples
GSM ID Sample info Characteristics Description
GSM312900 normal nasopharyngeal tissue, specimen N5 normal; Adjacent pair of T18 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312901 normal nasopharyngeal tissue, specimen N6 normal; Adjacent pair of T20 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312902 normal nasopharyngeal tissue, specimen N7 normal; Adjacent pair of T7 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312903 normal nasopharyngeal tissue, specimen N8 normal; Adjacent pair of T10 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312904 normal nasopharyngeal tissue, specimen N9 normal Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312905 normal nasopharyngeal tissue, specimen N10 normal Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312906 nasopharyngeal carcinoma, specimen T1 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T1N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312907 nasopharyngeal carcinoma, specimen T2 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T2N2 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312908 nasopharyngeal carcinoma, specimen T3 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T3N2 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312909 nasopharyngeal carcinoma, specimen T4 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T2N2 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312910 nasopharyngeal carcinoma, specimen T5 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T2N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312911 nasopharyngeal carcinoma, specimen T6 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T1N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312912 nasopharyngeal carcinoma, specimen T7 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T1N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312913 nasopharyngeal carcinoma, specimen T8 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T1N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312914 nasopharyngeal carcinoma, specimen T9 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T1N0 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312915 nasopharyngeal carcinoma, specimen T10 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T2N2 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312916 nasopharyngeal carcinoma, specimen T11 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T1N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312917 nasopharyngeal carcinoma, specimen T12 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T2N2 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312918 nasopharyngeal carcinoma, specimen T13 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T2N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312919 nasopharyngeal carcinoma, specimen T14 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T1N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312920 nasopharyngeal carcinoma, specimen T15 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T1N0 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312921 nasopharyngeal carcinoma, specimen T16 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T1N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312922 nasopharyngeal carcinoma, specimen T17 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T1N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312923 nasopharyngeal carcinoma, specimen T18 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T1N0 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312924 nasopharyngeal carcinoma, specimen T19 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T1N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312925 nasopharyngeal carcinoma, specimen T20 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T3N0 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312926 nasopharyngeal carcinoma, specimen T21 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T2N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312927 nasopharyngeal carcinoma, specimen T22 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T2N2 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312928 nasopharyngeal carcinoma, specimen T23 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T2N2 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312929 nasopharyngeal carcinoma, specimen T24 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T1N0 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312930 nasopharyngeal carcinoma, specimen T25 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T2N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312931 nasopharyngeal carcinoma, specimen T26 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T3N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312932 nasopharyngeal carcinoma, specimen T27 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T1N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312933 nasopharyngeal carcinoma, specimen T28 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T1N0 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312934 nasopharyngeal carcinoma, specimen T29 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T1N0 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312935 nasopharyngeal carcinoma, specimen T30 nasopharyngeal carcinoma; WHO histology:IIA; Tumor Stage:T2N1 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312936 nasopharyngeal carcinoma, specimen T31 nasopharyngeal carcinoma; WHO histology:IIB; Tumor Stage:T3N2 Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312896 normal nasopharyngeal tissue, specimen N1 normal; Biopsy Negative Control Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312897 normal nasopharyngeal tissue, specimen N2 normal; Biopsy Negative Control Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312898 normal nasopharyngeal tissue, specimen N3 normal; Biopsy Negative Control Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
GSM312899 normal nasopharyngeal tissue, specimen N4 normal; Biopsy Negative Control Total RNA extracted from laser-captured epithelium from 31 nasopharyngeal carcinomas and 10 normal healthy nasopharyngeal tissue specimens.
Platform GPL570  : [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Literature 17119049  16912175  22880099  
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* p<0.05 ** p<0.01