Gene Name	NECTIN3
Gene ID	25945
Gene Full Name	nectin cell adhesion molecule 3
Gene Alias	CD113|CDW113|NECTIN-3|PPR3|PRR3|PVRL3|PVRR3
Transcripts	ENSG00000177707
Virus	HIV
Gene Type	protein-coding
HPA Location Info	Cell Junctions, Cytosol;
Membrane Info	CD markers, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9NQS3
HGNC ID	HGNC:17664
OMIM ID	607147
Summary	This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001601	chr6	148	0	0	148	View
4001611	chr6	147	0	0	147	View
4011756	chr3	0	0	6	6	View
4012988	chr3	0	0	4	4	View

Data ID	Experiment type	Sample number	Platform
C   GSE30738	Chip-seq	2	Illumina Genome Analyzer II (Homo sapiens)
C   GSE220859	Chip-seq	11	Illumina NovaSeq 6000 (Homo sapiens)
GSE128121	RNA-seq	16	Illumina HiSeq 4000 (Homo sapiens)
GSE165708	RNA-seq	100	Illumina HiSeq 4000 (Homo sapiens)
C   GSE211651	Chip-seq;RNA-seq;PRO-seq	39	Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE162914	RNA-seq	211	Illumina HiSeq 2500 (Homo sapiens)
GSE144332	RNA-seq	75	NextSeq 550 (Homo sapiens)
C   GSE100376	ATAC-seq	24	Illumina NextSeq 500 (Homo sapiens)
GSE165132	RNA-seq	56	NextSeq 550 (Homo sapiens)
C   GSE165705	Chip-seq	30	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE144329	ATAC-seq	96	NextSeq 550 (Homo sapiens)
GSE205204	RNA-seq	14	Illumina NovaSeq 6000 (Homo sapiens)
GSE167211	RNA-seq	1	Illumina HiSeq 2000 (Homo sapiens)
GSE246082	RNA-seq	6	Illumina HiSeq 4000 (Homo sapiens)
C   GSE165703	ATAC-seq	82	Illumina HiSeq 4000 (Homo sapiens)
C   GSE100266	ATAC-seq;Chip-seq;RNA-seq	32	Illumina HiSeq 2500 (Homo sapiens)
GSE125686	RNA-seq	62	Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE164264	RNA-seq	6	BGISEQ-500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE30738 - NECTIN3 peak across samples

Peak Plot

> Dataset: GSE220859 - NECTIN3 peak across samples

Peak Plot

> Dataset: GSE211651 - NECTIN3 peak across samples

Peak Plot

> Dataset: GSE100376 - NECTIN3 peak across samples

Peak Plot

> Dataset: GSE165705 - NECTIN3 peak across samples

Peak Plot

> Dataset: GSE144329 - NECTIN3 peak across samples

Peak Plot

> Dataset: GSE165703 - NECTIN3 peak across samples

Peak Plot

> Dataset: GSE100266 - NECTIN3 peak across samples

Peak Plot