HIV Target gene Detail Information

> TOP6BL Gene Search Result


Gene Information
Gene Name TOP6BL
Gene ID 79703
Gene Full Name TOP6B like initiator of meiotic double strand breaks
Gene Alias C11orf80|HYDM4|TOPOVIBL
Transcripts ENSG00000173715
Virus HIV
Gene Type protein-coding
HPA Location Info Centrosome;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q8N6T0
HGNC ID HGNC:26197
OMIM ID 616109
Summary Predicted to be involved in meiotic DNA double-strand break formation and reciprocal meiotic recombination. Predicted to be located in chromosome. Implicated in gestational trophoblastic neoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [TOP6BL] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4008805 chr11 7 7 0 14 View
4009365 chr11 4 8 0 12 View
4011824 chr11 0 6 0 6 View
4012568 chr11 2 3 0 5 View
4012569 chr11 2 3 0 5 View
4012570 chr11 2 3 0 5 View

Target gene [TOP6BL] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE30738 		Chip-seq 2 Illumina Genome Analyzer II (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE144332 		RNA-seq 75 NextSeq 550 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE144332 - TOP6BL expression across samples

Volcano Plot

Bar Plot