HIV Target gene Detail Information

> DARS1 Gene Search Result


Gene Information
Gene Name DARS1
Gene ID 1615
Gene Full Name aspartyl-tRNA synthetase 1
Gene Alias DARS|HBSL|aspRS
Transcripts ENSG00000115866
Virus HIV
Gene Type protein-coding
HPA Location Info Cytosol;
Membrane Info Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID P14868
HGNC ID HGNC:2678
OMIM ID 603084
Summary This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Target gene [DARS1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001244 chr2 12 168 8 188 View
4009676 chr2 2 0 9 11 View
4009750 chr2 0 1 10 11 View
4011734 chr2 4 2 0 6 View
4012952 chr2 0 3 1 4 View
4015332 chr2 1 0 0 1 View

Target gene [DARS1] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE144332 		RNA-seq 75 NextSeq 550 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
C
  GSE30738 		Chip-seq 2 Illumina Genome Analyzer II (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE144332 - DARS1 expression across samples

Volcano Plot

Bar Plot