HIV Target gene Detail Information

> MTREX Gene Search Result


Gene Information
Gene Name MTREX
Gene ID 23517
Gene Full Name Mtr4 exosome RNA helicase
Gene Alias Dob1|KIAA0052|Mtr4|SKIV2L2|fSAP118
Transcripts ENSG00000039123
Virus HIV
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins
Uniport_ID P42285
HGNC ID HGNC:18734
OMIM ID 618122
Summary Enables ATP binding activity and RNA helicase activity. Involved in DNA damage response; RNA catabolic process; and maturation of 5.8S rRNA. Located in nuclear exosome (RNase complex) and nucleoplasm. Part of TRAMP complex and catalytic step 2 spliceosome. Biomarker of amyotrophic lateral sclerosis. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [MTREX] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001450 chr5 134 29 0 163 View
4003101 chr5 56 13 1 70 View
4003441 chr5 56 5 0 61 View
4009584 chr5 9 2 0 11 View
4012163 chr5 5 0 0 5 View

Target gene [MTREX] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE144332 RNA-seq 75 NextSeq 550 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
C
  GSE30738 		Chip-seq 2 Illumina Genome Analyzer II (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE187515 scRNA-seq 104 Illumina MiSeq (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE221688 - MTREX peak across samples

Peak Plot

> Dataset: GSE165705 - MTREX peak across samples

Peak Plot

> Dataset: GSE30738 - MTREX peak across samples

Peak Plot

> Dataset: GSE144329 - MTREX peak across samples

Peak Plot

> Dataset: GSE220859 - MTREX peak across samples

Peak Plot

> Dataset: GSE211651 - MTREX peak across samples

Peak Plot

> Dataset: GSE100376 - MTREX peak across samples

Peak Plot

> Dataset: GSE100266 - MTREX peak across samples

Peak Plot

> Dataset: GSE165703 - MTREX peak across samples

Peak Plot