HCMV Target gene Detail Information

> CASP2 Gene Search Result


Gene Information
Gene Name CASP2
Gene ID 835
Gene Full Name caspase 2
Gene Alias CASP-2|ICH1|MRT80|NEDD-2|NEDD2|PPP1R57
Transcripts ENSG00000106144
Virus HCMV
Gene Type protein-coding
HPA Location Info Nucleoplasm;Centrosome, Basal body, Cytosol;
Membrane Info Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P42575
HGNC ID HGNC:1503
OMIM ID 600639
Summary This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Target gene [CASP2] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 31427511 D275Y
gB
UL55
Cell line
T
 View

Target gene [CASP2] related to Omics data
Data ID Experiment type Sample number Platform
GSE152114 RNA-seq 4 Illumina HiSeq 2000 (Homo sapiens)
GSE280380 RNA-seq 54 Illumina NovaSeq 6000 (Homo sapiens)
GSE163707 RNA-seq 96 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (blank sample)
GSE168598 RNA-seq 154 Illumina HiSeq 3000 (Homo sapiens)
GSE248772 RNA-seq 84 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE164861 		Chip-seq;RNA-seq;ATAC-seq 79 Illumina NextSeq 500 (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens; Human betaherpesvirus 5);Illumina HiSeq 4000 (Human betaherpesvirus 5);Illumina NovaSeq 6000 (Human betaherpesvirus 5);Illumina HiSeq 4000 (Homo sapiens; Human betaherpesvirus 5)
GSE182788 RNA-seq 4 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE53271 		Chip-seq 2 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE185618 		Chip-seq 25 Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE193759 RNA-seq 12 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2000 (Homo sapiens; Human betaherpesvirus 5)
GSE94724 RNA-seq 4 Illumina HiSeq 2000 (Homo sapiens)
GSE254735 RNA-seq 4 Illumina NovaSeq 6000 (Homo sapiens)
GSE136217 RNA-seq 7 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens; Human betaherpesvirus 5)
GSE73853 RNA-seq 13 Illumina HiSeq 2000 (Homo sapiens)
GSE217832 RNA-seq 8 Illumina NextSeq 500 (Homo sapiens)
GSE164843 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens; Human betaherpesvirus 5)
C
  GSE254741 		ATAC-seq;ChIP-seq;HiChIP;RNA-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164839 RNA-seq 4 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens; Human betaherpesvirus 5)
C
  GSE171518 		Chip-seq 16 Illumina NovaSeq 6000 (Homo sapiens; Human betaherpesvirus 5)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE164861 - CASP2 peak across samples

Peak Plot

> Dataset: GSE53271 - CASP2 peak across samples

Peak Plot

> Dataset: GSE185618 - CASP2 peak across samples

Peak Plot

> Dataset: GSE254741 - CASP2 peak across samples

Peak Plot

> Dataset: GSE171518 - CASP2 peak across samples

Peak Plot