Virus Dataset Detail

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Dataset Information
Accession GSE73853
Status 2016/9/17
Title Transcriptome analysis of diverse cell types infected with human cytomegalovirus [RNA-Seq]
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Comprehensive RNA sequencing and splicing-sensitive microarray analysis of three diverse cell types infected with human cytomegalovirus (HCMV), including primary fibroblasts (HFFs), endothelial cells (ECs), and neural progenitors (NPCs) derived from embryonic stem cells. This global analysis includes both host and viral gene expression measurements, and an in-depth assessment of alternative RNA processing events. Extended comparisons were conducted through RNA sequencing analysis of human herpes simplex virus (HSV)-2 and human immunodeficiency virus type 1 (HIV-1) infections.
Samples
GSM ID Sample info Characteristics Description
GSM1904488 HFF_Mock_48h cell type:HFF cells; infection:mock; time:48h Sequencing Sample 1
GSM1904489 HFF_InfectedHCMVTB40E_48h cell type:HFF cells; infection:HCMV (strain TB40E); time:48h Sequencing Sample 2
GSM1904490 HFF_InfectedHCMVTB40E_96h cell type:HFF cells; infection:HCMV (strain TB40E); time:96h Sequencing Sample 3
GSM1904491 EC_Mock_48h cell type:EC cells; infection:mock; time:48h Sequencing Sample 4
GSM1904492 EC_InfectedHCMVTB40E_48h cell type:EC cells; infection:HCMV (strain TB40E); time:48h Sequencing Sample 5
GSM1904493 EC_InfectedHCMVTB40E_96h cell type:EC cells; infection:HCMV (strain TB40E); time:96h Sequencing Sample 6
GSM1904494 NPC_Mock_48h cell type:NPC cells (ES-derived); infection:mock; time:48h Sequencing Sample 7
GSM1904495 NPC_InfectedHCMVTB40E_48h cell type:NPC cells (ES-derived); infection:HCMV (strain TB40E); time:48h Sequencing Sample 8
GSM1904496 NPC_InfectedHCMVTB40E_96h cell type:NPC cells (ES-derived); infection:HCMV (strain TB40E); time:96h Sequencing Sample 9
GSM1904497 HFF_MockforHSV_8h cell type:HFF cells; infection:mock; time:8h Sequencing Sample 10
GSM1904498 HFF_InfectedHSV2_8h cell type:HFF cells; infection:HSV2; time:8h Sequencing Sample 11
GSM2306702 Tcell_Control_5d cell type:T cells; infection:control; time:5d -
GSM2306703 Tcell_InfectedHIV1_5d cell type:T cells; infection:HIV1; time:5d -
Platform GPL11154  : Illumina HiSeq 2000 (Homo sapiens)
Literature 27775709  
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xCell Plot
* p<0.05 ** p<0.01