Virus Dataset Detail

> Detail information for each sample

Dataset Information
Accession GSE161783
Status 2022/8/18
Title Transcriptomic and epigenetic investigation of Zika virus (ZIKV) infection in human monocyte-derived dendritic cells and other cell types
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing;Genome binding/occupancy profiling by high throughput sequencing
Summary Dendritic cells are key targets for ZIKV infection. To identify host pathways manipulated by ZIKV in dendritic cells, we developed a system that enables characterization of genome-wide transcriptional and epigenetic changes in ZIKV-infected and neighboring, uninfected primary human dendritic cells.
Samples
GSM ID Sample info Characteristics Description
GSM4914439 Human2_RNAseq_Mock_24h donor id:Human2; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC2_Mock_RNAseq
GSM4914440 Human2_RNAseq_ZIKVnegative_24h donor id:Human2; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC2_ZIKVNeg_RNAseq
GSM4914441 Human2_RNAseq_ZIKVpositive_24h donor id:Human2; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC2_ZIKVPos_RNAseq
GSM4914436 Human1_RNAseq_Mock_24h donor id:Human1; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC1_Mock_RNAseq
GSM4914442 Human3_RNAseq_Mock_24h donor id:Human3; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC3_Mock_RNAseq
GSM4914443 Human3_RNAseq_ZIKVnegative_24h donor id:Human3; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC3_ZIKVNeg_RNAseq
GSM4914444 Human3_RNAseq_ZIKVpositive_24h donor id:Human3; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC3_ZIKVPos_RNAseq
GSM4914445 Human4_RNAseq_Mock_24h donor id:Human4; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC4_Mock_RNAseq
GSM4914446 Human4_RNAseq_ZIKVnegative_24h donor id:Human4; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC4_ZIKVneg_RNAseq
GSM4914437 Human1_RNAseq_ZIKVnegative_24h donor id:Human1; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC1_ZIKVNeg_RNAseq
GSM4914438 Human1_RNAseq_ZIKVpositive_24h donor id:Human1; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC1_ZIKVPos_RNAseq
GSM4914464 Human5_input_ChIPseq_ZIKVnegative_24h donor id:Human5; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-PRVABC59; chip antibody:input; time post infection viral infection:24h; experment type:input hDC5_ZIKVneg_SERBP_input
GSM4914465 Human5_input_ChIPseq_ZIKVpositive_24h donor id:Human5; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-PRVABC59; chip antibody:input; time post infection viral infection:24h; experment type:input hDC5_ZIKVpos_SREBP_input.gz
GSM4914447 Human4_RNAseq_ZIKVpositive_24h donor id:Human4; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:Ribosome-depleted RNA-seq processed data file: RNAseq_moDC_ZIKV_24h_FPKM.txt;hDC4_ZIKVpos_RNAseq
GSM4914448 Human1_csRNAseq_Mock_24h donor id:Human1; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:capped-small RNA-seq (csRNA-seq) processed data file: Mock_csRNAseq_TSS.bed;hDC1_Mock_csRNAseq
GSM4914449 Human1_csRNAseq_ZIKVnegative_24h donor id:Human1; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:capped-small RNA-seq (csRNA-seq) processed data file: ZIKVneg_csRNAseq_TSS.bed;hDC1_ZIKVneg_csRNAseq
GSM4914450 Human1_csRNAseq_ZIKVpositive_24h donor id:Human1; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:capped-small RNA-seq (csRNA-seq) processed data file: ZIKVpos_csRNAseq_TSS.bed;hDC1_ZIKVpos_csRNAseq
GSM4914466 Human6_SREBP_ChIPseq_Mock_24h donor id:Human6; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-PRVABC59; chip antibody:SREBP antibodies (Santa Cruz Biotechnology: sc-8984X, Thermo Fisher Scientific: PA1-337, R&D Systems: AF7119); time post infection viral infection:24h; experment type:SREBP ChIP-seq hDC6_Mock_SREBP_input
GSM4914451 Human2_csRNAseq_Mock_24h donor id:Human2; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:capped-small RNA-seq (csRNA-seq) processed data file: Mock_csRNAseq_TSS.bed;hDC2_Mock_csRNAseq
GSM4914452 Human2_csRNAseq_ZIKVnegative_24h donor id:Human2; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:capped-small RNA-seq (csRNA-seq) processed data file: ZIKVneg_csRNAseq_TSS.bed;hDC2_ZIKVneg_csRNAseq
GSM4914467 Human6_SREBP_ChIPseq_ZIKVnegative_24h donor id:Human6; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-PRVABC59; chip antibody:SREBP antibodies (Santa Cruz Biotechnology: sc-8984X, Thermo Fisher Scientific: PA1-337, R&D Systems: AF7119); time post infection viral infection:24h; experment type:SREBP ChIP-seq hDC6_ZIKVneg_SREBP
GSM4914453 Human2_csRNAseq_ZIKVpositive_24h donor id:Human2; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:capped-small RNA-seq (csRNA-seq) processed data file: ZIKVpos_csRNAseq_TSS.bed;hDC2_ZIKVpos_csRNAseq
GSM4914468 Human6_SREBP_ChIPseq_ZIKVpositive_24h donor id:Human6; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-PRVABC59; chip antibody:SREBP antibodies (Santa Cruz Biotechnology: sc-8984X, Thermo Fisher Scientific: PA1-337, R&D Systems: AF7119); time post infection viral infection:24h; experment type:SREBP ChIP-seq hDC6_ZIKVpos_SREBP
GSM4914454 Human3_csRNAseq_Mock_24h donor id:Human3; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:capped-small RNA-seq (csRNA-seq) processed data file: Mock_csRNAseq_TSS.bed;hDC3_Mock_csRNAseq
GSM4914469 Human6_input_ChIPseq_Mock_24h donor id:Human6; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-PRVABC59; chip antibody:input; time post infection viral infection:24h; experment type:input hDC6_Mock_SREBP
GSM4914455 Human3_csRNAseq_ZIKVnegative_24h donor id:Human3; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:capped-small RNA-seq (csRNA-seq) processed data file: ZIKVneg_csRNAseq_TSS.bed;hDC3_ZIKVneg_csRNAseq
GSM4914456 Human3_csRNAseq_ZIKVpositive_24h donor id:Human3; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:capped-small RNA-seq (csRNA-seq) processed data file: ZIKVpos_csRNAseq_TSS.bed;hDC3_ZIKVpos_csRNAseq
GSM4914457 Human3_csRNAseqinput_Mock_24h donor id:Human3; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:input (csRNA-seq) hDC3_Mock_csRNAseq_input
GSM4914458 Human3_csRNAseqinput_ZIKVneg_24h donor id:Human3; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:input (csRNA-seq) hDC3_ZIKVneg_csRNAseq_input
GSM4914459 Human3_csRNAseqinput_ZIKVpos_24h donor id:Human3; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-SD001; time post infection viral infection:24h; experment type:input (csRNA-seq) hDC3_ZIKVpos_csRNAseq_input
GSM4914460 Human5_SREBP_ChIPseq_Mock_24h donor id:Human5; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-PRVABC59; chip antibody:SREBP antibodies (Santa Cruz Biotechnology: sc-8984X, Thermo Fisher Scientific: PA1-337, R&D Systems: AF7119); time post infection viral infection:24h; experment type:SREBP ChIP-seq hDC5_Mock_SREBP_input
GSM4914470 Human6_input_ChIPseq_ZIKVnegative_24h donor id:Human6; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-PRVABC59; chip antibody:input; time post infection viral infection:24h; experment type:input hDC6_ZIKVneg_SREBP_input
GSM4914461 Human5_SREBP_ChIPseq_ZIKVnegative_24h donor id:Human5; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-PRVABC59; chip antibody:SREBP antibodies (Santa Cruz Biotechnology: sc-8984X, Thermo Fisher Scientific: PA1-337, R&D Systems: AF7119); time post infection viral infection:24h; experment type:SREBP ChIP-seq hDC5_ZIKVneg_SREBP
GSM4914471 Human6_input_ChIPseq_ZIKVpositive_24h donor id:Human6; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-PRVABC59; chip antibody:input; time post infection viral infection:24h; experment type:input hDC6_ZIKVpos_SREBP_input
GSM4914462 Human5_SREBP_ChIPseq_ZIKVpositive_24h donor id:Human5; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-PRVABC59; chip antibody:SREBP antibodies (Santa Cruz Biotechnology: sc-8984X, Thermo Fisher Scientific: PA1-337, R&D Systems: AF7119); time post infection viral infection:24h; experment type:SREBP ChIP-seq hDC5_ZIKVpos_SREBP
GSM4914472 Human7_SREBP_ChIPseq_Mock_24h donor id:Human7; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-PRVABC59; chip antibody:SREBP antibodies (Santa Cruz Biotechnology: sc-8984X, Thermo Fisher Scientific: PA1-337, R&D Systems: AF7119); time post infection viral infection:24h; experment type:SREBP ChIP-seq hDC7_Mock_SREBP
GSM4914463 Human5_input_ChIPseq_Mock_24h donor id:Human5; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-PRVABC59; chip antibody:input; time post infection viral infection:24h; experment type:input hDC5_Mock_SREBP
GSM4914473 Human7_SREBP_ChIPseq_ZIKVnegative_24h donor id:Human7; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-PRVABC59; chip antibody:SREBP antibodies (Santa Cruz Biotechnology: sc-8984X, Thermo Fisher Scientific: PA1-337, R&D Systems: AF7119); time post infection viral infection:24h; experment type:SREBP ChIP-seq hDC7_ZIKVneg_SREBP
GSM4914474 Human7_SREBP_ChIPseq_ZIKVpositive_24h donor id:Human7; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-PRVABC59; chip antibody:SREBP antibodies (Santa Cruz Biotechnology: sc-8984X, Thermo Fisher Scientific: PA1-337, R&D Systems: AF7119); time post infection viral infection:24h; experment type:SREBP ChIP-seq hDC7_ZIKVpos_SREBP
GSM4914475 Human7_input_ChIPseq_Mock_24h donor id:Human7; cell type:monocyte-derived dendritic cell; viral infection:mock infected; viral strain:ZIKV-PRVABC59; chip antibody:input; time post infection viral infection:24h; experment type:input hDC7_Mock_SREBP_input
GSM4914476 Human7_input_ChIPseq_ZIKVnegative_24h donor id:Human7; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-bystander; viral strain:ZIKV-PRVABC59; chip antibody:input; time post infection viral infection:24h; experment type:input hDC7_ZIKVneg_SREBP_input
GSM4914477 Human7_input_ChIPseq_ZIKVpositive_24h donor id:Human7; cell type:monocyte-derived dendritic cell; viral infection:ZIKV-infected; viral strain:ZIKV-PRVABC59; chip antibody:input; time post infection viral infection:24h; experment type:input hDC7_ZIKVpos_SREBP_input
GSM6474698 Huh7.5_1_RNAseq_Mock_24h cell type:Hepatocyte cell line; viral infection:mock infected; viral strain:ZIKV-PRVABC59; time post infection viral infection:24h Ribosome-depleted RNA-seq
GSM6474699 Huh7.5_2_RNAseq_Mock_24h cell type:Hepatocyte cell line; viral infection:mock infected; viral strain:ZIKV-PRVABC59; time post infection viral infection:24h Ribosome-depleted RNA-seq
GSM6474700 Huh7.5_1_RNAseq_ZIKVneg_24h cell type:Hepatocyte cell line; viral infection:ZIKV-bystander; viral strain:ZIKV-PRVABC59; time post infection viral infection:24h Ribosome-depleted RNA-seq
GSM6474701 Huh7.5_2_RNAseq_ZIKVneg_24h cell type:Hepatocyte cell line; viral infection:ZIKV-bystander; viral strain:ZIKV-PRVABC59; time post infection viral infection:24h Ribosome-depleted RNA-seq
GSM6474702 Huh7.5_1_RNAseq_ZIKVpos_24h cell type:Hepatocyte cell line; viral infection:ZIKV-infected; viral strain:ZIKV-PRVABC59; time post infection viral infection:24h Ribosome-depleted RNA-seq
GSM6474703 Huh7.5_2_RNAseq_ZIKVpos_24h cell type:Hepatocyte cell line; viral infection:ZIKV-infected; viral strain:ZIKV-PRVABC59; time post infection viral infection:24h Ribosome-depleted RNA-seq
GSM6474704 NPC_RNAseq_Mock_24h donor:WT-126; cell type:iPSC Neural progenitor cell; viral infection:mock infected; viral strain:ZIKV-PRVABC59; time post infection viral infection:24h Ribosome-depleted RNA-seq
GSM6474705 NPC_RNAseq_ZIKVneg_24h donor:WT-126; cell type:iPSC Neural progenitor cell; viral infection:ZIKV-bystander; viral strain:ZIKV-PRVABC59; time post infection viral infection:24h Ribosome-depleted RNA-seq
GSM6474706 NPC_RNAseq_ZIKVpos_24h donor:WT-126; cell type:iPSC Neural progenitor cell; viral infection:ZIKV-infected; viral strain:ZIKV-PRVABC59; time post infection viral infection:24h Ribosome-depleted RNA-seq
Platform GPL18573  GPL20301  GPL24676  : Illumina NextSeq 500 (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
Literature 36097162  
Download Download xCell Data  Download Expression Analysis Data  Download Genome Binding/Occupancy Profiling Analysis Data
xCell Plot
* p<0.05 ** p<0.01