Accession	GSE185241
Status	2023/6/20
Title	The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes
Organism	Homo sapiens
Experiment type	Expression profiling by high throughput sequencing;Genome binding/occupancy profiling by high throughput sequencing
Summary	This SuperSeries is composed of the following SubSeries: GSE185234 The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes (ATAC-seq I) GSE185235 The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes (ATAC-seq II) GSE185236 The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes (Omni-ATAC-seq II) GSE185238 The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes (Omni-ATAC-seq I) GSE185240 The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes (Omni-ATAC-seq III) GSE185246 The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes (ChIPmentation) GSE208077 The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes (OMNI-ATAC-seq IV) GSE208078 The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes (RNA-seq II)
Samples	GSM ID Sample info Characteristics Description GSM5608518 mock infection, replicate 1 infection status:N/A; virus strain:N/A followed ATACseq protocol GSM5608519 mock infection, replicate 2 infection status:N/A; virus strain:N/A followed ATACseq protocol GSM5608520 HSV-1 wt, strain 17, replicate 1 infection status:8 hpi; virus strain:strain 17 followed ATACseq protocol GSM5608521 HSV-1 wt, strain 17, replicate 2 infection status:8 hpi; virus strain:strain 17 followed ATACseq protocol GSM5608522 HSV-1 wt, strain 17, +PAA, replicate 1 infection status:8 hpi; treatment:PAA 300ug/ml; virus strain:strain 17 followed ATACseq protocol GSM5608523 HSV-1 wt, strain 17, +PAA, replicate 2 infection status:8 hpi; treatment:PAA 300ug/ml; virus strain:strain 17 followed ATACseq protocol GSM5608524 HSV-1 lacking expression of ICP0, replicate 1 infection status:12 hpi; virus strain:strain 17, dl1403 followed ATACseq protocol GSM5608525 HSV-1 lacking expression of ICP0, replicate 2 infection status:12 hpi; virus strain:strain 17, dl1403 followed ATACseq protocol GSM5608526 HSV-1 lacking expression of ICP22, HSV-1 strain F mutant R325, replicate 1 infection status:12 hpi; virus strain:strain F, R325 followed ATACseq protocol GSM5608527 HSV-1 lacking expression of ICP22, HSV-1 strain F mutant R325, replicate 2 infection status:12 hpi; virus strain:strain F, R325 followed ATACseq protocol GSM5608528 HSV-1 lacking expression of ICP22, HSV-1 strain F mutant R325, replicate 3 infection status:12 hpi; virus strain:strain F, R325 followed ATACseq protocol GSM5608529 HSV-1 lacking expression of ICP22, HSV-1 strain F mutant R325, replicate 4 infection status:12 hpi; virus strain:strain F, R325 followed ATACseq protocol GSM5608530 HSV-1 lacking expression of ICP22, HSV-1 strain F mutant R325, +PAA, replicate 1 infection status:12 hpi; treatment:PAA 300ug/ml; virus strain:strain F, R325 followed ATACseq protocol GSM5608531 HSV-1 lacking expression of ICP22, HSV-1 strain F mutant R325, +PAA, replicate 2 infection status:12 hpi; treatment:PAA 300ug/ml; virus strain:strain F, R325 followed ATACseq protocol GSM5608532 HSV-1 lacking expression of ICP27, KOS, replicate 1 infection status:8 hpi; virus strain:strain KOS, 27LacZ followed ATACseq protocol GSM5608533 HSV-1 lacking expression of ICP27, KOS, replicate 2 infection status:8 hpi; virus strain:strain KOS, 27LacZ followed ATACseq protocol GSM5608534 HSV-1 lacking expression of UL41, replicate 1 infection status:8 hpi; virus strain:strain 17 followed ATACseq protocol GSM5608535 HSV-1 lacking expression of UL41, replicate 2 infection status:8 hpi; virus strain:strain 17 followed ATACseq protocol GSM5608578 T-HF cells, with no SSRP1 KD, infected with WT strain F, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml); agent:Herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608579 T-HF cells, with no SSRP1 KD, infected with WT strain F, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml); agent:Herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608536 HFFF cells infected with ICP22-null mutant (12 hpi), replicate 1 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:12 hpi; treatment:no treatment; agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM5608580 T-HF cells, with SSRP1 KD, infected with WT strain F, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:Herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM6336819 HFF-tert dox-inducible ICP22, no dox, 200mM KCl for 2h, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:no doxycycline, 200mM KCl for 2h ICP22_no_dox_KCl_rep2;ICP22/27 OE, salt stress GSM5608537 HFFF cells infected with ICP22-null mutant (12 hpi), replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:12 hpi; treatment:no treatment; agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM5608720 HFFF cells mock 8h infected, PAA treated, histone H1, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM6336820 HFF-tert dox-inducible ICP22, no dox, no KCl, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:no doxycycline, no KCl ICP22_no_dox_rep1;ICP22/27 OE, salt stress GSM6336821 HFF-tert dox-inducible ICP22, no dox, no KCl, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:no doxycycline, no KCl ICP22_no_dox_rep2;ICP22/27 OE, salt stress GSM5608581 T-HF cells, with SSRP1 KD, infected with WT strain F, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:Herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608600 HA-ICP22+V5-ICP27 cells, DOX, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; treatment:DOX (5 ug/mL); treatment 2:no treatment DNA isolated with MinElute PCR Purification Kit GSM5608601 HA-ICP22+V5-ICP27 cells, no DOX, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; treatment:no treatment; treatment 2:no treatment DNA isolated with MinElute PCR Purification Kit GSM5608538 HFFF cells infected with ICP22-null mutant (8 hpi), replicate 1 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:8 hpi; treatment:no treatment; agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM5608602 HA-ICP22+V5-ICP27 cells, DOX, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; treatment:DOX (5 ug/mL); treatment 2:no treatment DNA isolated with MinElute PCR Purification Kit GSM5608603 HA-ICP22+V5-ICP27 cells, no DOX, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; treatment:no treatment; treatment 2:no treatment DNA isolated with MinElute PCR Purification Kit GSM5608604 HA-ICP22 cells, salt stress, DOX, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; treatment:DOX (5 ug/mL); treatment 2:80 mM KCl DNA isolated with MinElute PCR Purification Kit GSM5608605 HA-ICP22 cells, salt stress, no DOX, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; treatment:no treatment; treatment 2:80 mM KCl DNA isolated with MinElute PCR Purification Kit GSM5608721 HFFF cells mock 8h infected, PAA treated, histone H3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608606 HA-ICP22 cells, salt stress, DOX, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; treatment:DOX (5 ug/mL); treatment 2:80 mM KCl DNA isolated with MinElute PCR Purification Kit GSM5608722 HFFF cells mock 8h infected, PAA treated, histone H3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608607 HA-ICP22 cells, salt stress, no DOX, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; treatment:no treatment; treatment 2:80 mM KCl DNA isolated with MinElute PCR Purification Kit GSM5608723 HFFF cells mock 8h infected, PAA treated, histone H4, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608608 primary HFFF cells, Mock-infected, PAA 350ug/ml, replicate 1 cell type:primary Human Foetal Foreskin Fibroblast cells; treatment:350 ug'/ml PAA; treatment 2:Mock DNA isolated with MinElute PCR Purification Kit GSM5608724 HFFF cells mock 8h infected, PAA treated, histone H4, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608725 HFFF cells mock 8h infected, PAA treated, histone H3K27me3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608609 primary HFFF cells, Mock infected, PAA 350ug/ml, replicate 2 cell type:primary Human Foetal Foreskin Fibroblast cells; treatment:350 ug'/ml PAA; treatment 2:Mock DNA isolated with MinElute PCR Purification Kit GSM5608726 HFFF cells mock 8h infected, PAA treated, histone H3K27me3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608610 primary HFFF cells, infected with KOS 1.1 strain, PAA 350ug/ml, replicate 1 cell type:primary Human Foetal Foreskin Fibroblast cells; treatment:350 ug'/ml PAA; treatment 2:WT KOS 1.1 DNA isolated with MinElute PCR Purification Kit GSM5608727 HFFF cells mock 8h infected, PAA treated, histone H3K36me3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608539 HFFF cells infected with ICP22-null mutant (8 hpi), replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:8 hpi; treatment:no treatment; agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM5608611 primary HFFF cells, infected with KOS 1.1 strain, PAA 350ug/ml, replicate 2 cell type:primary Human Foetal Foreskin Fibroblast cells; treatment:350 ug'/ml PAA; treatment 2:WT KOS 1.1 DNA isolated with MinElute PCR Purification Kit GSM5608728 HFFF cells mock 8h infected, PAA treated, histone H3K36me3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608612 primary HFFF cells, infected with KOS 1.1 strain derived US1 knock-out, PAA 350ug/ml, replicate 1 cell type:primary Human Foetal Foreskin Fibroblast cells; treatment:350 ug'/ml PAA; treatment 2:KOS 1.1 with US1 deletion DNA isolated with MinElute PCR Purification Kit GSM5608729 HFFF cells infected with HSV-1 WT (F), 8hpi, PAA treated, histone H1, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608613 primary HFFF cells, infected with KOS 1.1 strain derived US1 knock-out, PAA 350ug/ml, replicate 2 cell type:primary Human Foetal Foreskin Fibroblast cells; treatment:350 ug'/ml PAA; treatment 2:KOS 1.1 with US1 deletion DNA isolated with MinElute PCR Purification Kit GSM5608540 HFFF cells infected with ICP22-null mutant (12 hpi), treated with PAA, replicate 1 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:12 hpi; treatment:PAA (350 ug/ml); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM5608730 HFFF cells infected with HSV-1 WT (F), 8hpi, PAA treated, histone H1, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608644 GFP-expressing HH-TERT cells, infected with US1 deletion mutant HSV-1 strain 17, 8 hpi, replicate 1 cell line:HFF-TERT cells doxycycline-inducibly expressing GFP (control sample); virus strain:HSV-1(17+)Lox BAC derived US1 deletion mutant; agent:infected with US1 mutant - GSM5608731 HFFF cells infected with deltaICP22 (F), 8hpi, PAA treated, histone H1, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:deltaICP22, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608645 GFP-expressing HH-TERT cells, infected with US1 deletion mutant HSV-1 strain 17, 8 hpi, replicate 2 cell line:HFF-TERT cells doxycycline-inducibly expressing GFP (control sample); virus strain:HSV-1(17+)Lox BAC derived US1 deletion mutant; agent:infected with US1 mutant - GSM5608732 HFFF cells infected with deltaICP22 (F), 8hpi, PAA treated, histone H1, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:deltaICP22, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608541 HFFF cells infected with ICP22-null mutant (12 hpi), treated with PAA, replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:12 hpi; treatment:PAA (350 ug/ml); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM5608646 GFP-expressing HH-TERT cells, mock-infected, 8 hpi, replicate 1 cell line:HFF-TERT cells doxycycline-inducibly expressing GFP (control sample); virus strain:N/A; agent:mock infected - GSM5608733 HFFF cells mock infected, PAA treated, histone H1, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608647 GFP-expressing HH-TERT cells, mock-infected, 8 hpi, replicate 2 cell line:HFF-TERT cells doxycycline-inducibly expressing GFP (control sample); virus strain:N/A; agent:mock infected - GSM5608542 HFFF cells infected with ICP22-null mutant (8 hpi), treated with PAA, replicate 1 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:8 hpi; treatment:PAA (350 ug/ml); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM5608648 GFP-expressing HH-TERT cells, infected with BAC-derived WT HSV-1 strain 17, 8 hpi, replicate 1 cell line:HFF-TERT cells doxycycline-inducibly expressing GFP (control sample); virus strain:HSV-1(17+)Lox BAC derived WT virus; agent:infected with parental BAC derived wt virus - GSM5608734 HFFF cells mock infected, PAA treated, histone H1, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608649 GFP-expressing HH-TERT cells, infected with BAC-derived WT HSV-1 strain 17, 8 hpi, replicate 2 cell line:HFF-TERT cells doxycycline-inducibly expressing GFP (control sample); virus strain:HSV-1(17+)Lox BAC derived WT virus; agent:infected with parental BAC derived wt virus - GSM5608735 HFFF cells mock infected, histone H3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608709 HFFF cells infected with HSV-1 WT (17), 8hpi, PAA treated, histone H1, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608543 HFFF cells infected with ICP22-null mutant (8 hpi), treated with PAA, replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:8 hpi; treatment:PAA (350 ug/ml); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM5608710 HFFF cells infected with HSV-1 WT (17), 8hpi, PAA treated, histone H1, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608544 HFFF cells mock infected (12 hpi), replicate 1 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:no infection; treatment:no treatment; agent:no infection DNA isolated with MinElute PCR Purification Kit GSM5608711 HFFF cells infected with HSV-1 WT (17), 8hpi, PAA treated, histone H3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608712 HFFF cells infected with HSV-1 WT (17), 8hpi, PAA treated, histone H3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608545 HFFF cells mock infected (12 hpi), replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:no infection; treatment:no treatment; agent:no infection DNA isolated with MinElute PCR Purification Kit GSM5608713 HFFF cells infected with HSV-1 WT (17), 8hpi, PAA treated, histone H4, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608736 HFFF cells mock infected, histone H3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608714 HFFF cells infected with HSV-1 WT (17), 8hpi, PAA treated, histone H4, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608737 HFFF cells infected with HSV-1 WT (17), histone H3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608546 HFFF cells mock infected (12 hpi), treated with PAA, replicate 1 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:no infection; treatment:PAA (350 ug/ml); agent:no infection DNA isolated with MinElute PCR Purification Kit GSM5608715 HFFF cells infected with HSV-1 WT (17), 8hpi, PAA treated, histone H3K27me3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608738 HFFF cells infected with HSV-1 WT (17), histone H3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608739 HFFF cells mock infected, histone H3K27me3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608547 HFFF cells mock infected (12 hpi), treated with PAA, replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:no infection; treatment:PAA (350 ug/ml); agent:no infection DNA isolated with MinElute PCR Purification Kit GSM5608740 HFFF cells mock infected, histone H3K27me3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608548 HFFF cells mock infected (8 hpi), replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:no infection; treatment:no treatment; agent:no infection DNA isolated with MinElute PCR Purification Kit GSM5608741 HFFF cells infected with HSV-1 WT (17), histone H3K27me3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608716 HFFF cells infected with HSV-1 WT (17), 8hpi, PAA treated, histone H3K27me3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM6336822 HFF-tert dox-inducible ICP27, 5ug/ml dox for 24h, no KCl, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP27 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:5ug/ml doxycycline for 24h, no KCl ICP27_dox_rep1;ICP22/27 OE, salt stress GSM5608549 HFFF cells mock infected (8 hpi), treated with PAA, replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:no infection; treatment:PAA (350 ug/ml); agent:no infection DNA isolated with MinElute PCR Purification Kit GSM5608717 HFFF cells infected with HSV-1 WT (17), 8hpi, PAA treated, histone H3K36me3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608742 HFFF cells infected with HSV-1 WT (17), histone H3K27me3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608718 HFFF cells infected with HSV-1 WT (17), 8hpi, PAA treated, histone H3K36me3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM6336823 HFF-tert dox-inducible ICP27, 5ug/ml dox for 24h, no KCl, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP27 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:5ug/ml doxycycline for 24h, no KCl ICP27_dox_rep2;ICP22/27 OE, salt stress GSM5608550 HFFF cells infected with HSV-1 WT (12 hpi), replicate 1 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:12 hpi; treatment:no treatment; agent:Herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM5608719 HFFF cells mock 8h infected, PAA treated, histone H1, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:PAA (350 microg/ml); infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608743 HFFF cells mock infected, histone H3K36me3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM6336812 HFF-tert, doxycycline-inducible ICP27, no treatment, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP27 cassette and rtTA3; treatment:no treatment ICP27_no_dox_R1 GSM6336824 HFF-tert dox-inducible ICP27, no dox, no KCl, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP27 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:no doxycycline, no KCl ICP27_no_dox_rep1;ICP22/27 OE, salt stress GSM5608551 HFFF cells infected with HSV-1 WT (12 hpi), replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:12 hpi; treatment:no treatment; agent:Herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM5608744 HFFF cells mock infected, histone H3K36me3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM6336825 HFF-tert dox-inducible ICP27, no dox, no KCl, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP27 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:no doxycycline, no KCl ICP27_no_dox_rep2;ICP22/27 OE, salt stress GSM5608745 HFFF cells mock infected, histone H3K36me3, replicate 3 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:mock DNA isolated with Zymo DNA Clean & Concentrator GSM5608746 HFFF cells infected with HSV-1 WT (17), histone H3K36me3, replicate 1 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608552 HFFF cells infected with HSV-1 WT (12 hpi), treated with PAA, replicate 1 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:12 hpi; treatment:PAA (350 ug/ml); agent:Herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM6336826 HFF-tert dox-inducible amiRNA1 Mock, +PAA, 8 hpi, Mock, no dox, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA1); time post_infection:Mock, +PAA, 8 hpi; infection:Mock; treatment:no doxycycline, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) Mock_minus_dox_rep1;SSRP1 KD GSM6336813 HFF-tert, doxycycline-inducible ICP27, no treatment, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP27 cassette and rtTA3; treatment:no treatment ICP27_no_dox_R2 GSM5608747 HFFF cells infected with HSV-1 WT (17), histone H3K36me3, replicate 2 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608553 HFFF cells infected with HSV-1 WT (12 hpi), treated with PAA, replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:12 hpi; treatment:PAA (350 ug/ml); agent:Herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM6336814 HFF-tert dox-inducible ICP22, 5ug/ml dox for 24h, 200mM KCl for 2h, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:5ug/ml doxycycline for 24h, 200mM KCl for 2h ICP22_dox_KCl_rep1;ICP22/27 OE, salt stress GSM6336827 HFF-tert dox-inducible amiRNA2 Mock, +PAA, 8 hpi, Mock, no dox, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA2); time post_infection:Mock, +PAA, 8 hpi; infection:Mock; treatment:no doxycycline, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) Mock_minus_dox_rep2;SSRP1 KD GSM6336815 HFF-tert dox-inducible ICP22, 5ug/ml dox for 24h, 200mM KCl for 2h, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:5ug/ml doxycycline for 24h, 200mM KCl for 2h ICP22_dox_KCl_rep2;ICP22/27 OE, salt stress GSM5608554 HFFF cells infected with HSV-1 WT (8 hpi), replicate 1 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:8 hpi; treatment:no treatment; agent:Herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM6336816 HFF-tert dox-inducible ICP22, 5ug/ml dox for 24h, no KCl, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:5ug/ml doxycycline for 24h, no KCl ICP22_dox_rep1;ICP22/27 OE, salt stress GSM6336817 HFF-tert dox-inducible ICP22, 5ug/ml dox for 24h, no KCl, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:5ug/ml doxycycline for 24h, no KCl ICP22_dox_rep2;ICP22/27 OE, salt stress GSM5608555 HFFF cells infected with HSV-1 WT (8 hpi), replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:8 hpi; treatment:no treatment; agent:Herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM6336818 HFF-tert dox-inducible ICP22, no dox, 200mM KCl for 2h, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; time post_infection:N/A; infection:N/A; treatment:no doxycycline, 200mM KCl for 2h ICP22_no_dox_KCl_rep1;ICP22/27 OE, salt stress GSM5608556 HFFF cells infected with HSV-1 WT (8 hpi), treated with PAA, replicate 1 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:8 hpi; treatment:PAA (350 ug/ml); agent:Herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM5608748 HFFF cells infected with HSV-1 WT (17), histone H3K36me3, replicate 3 cell type:Human fetal foreskin fibroblasts; treatment:no treatment; infection:HSV-1 WT, strain 17 DNA isolated with Zymo DNA Clean & Concentrator GSM5608557 HFFF cells infected with HSV-1 WT (8 hpi), treated with PAA, replicate 2 cell type:Primary human fetal foreskin fibroblasts (HFFF); time post infection:8 hpi; treatment:PAA (350 ug/ml); agent:Herpes simplex virus 1, strain F DNA isolated with MinElute PCR Purification Kit GSM6336802 HFF-tert, doxycycline-inducible ICP22, 5ug/ml doxycycline for 24h, 200mM KCl for 2h, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; treatment:5ug/ml doxycycline for 24h, 200mM KCl for 2h ICP22_dox_KCl_R1 GSM6336828 HFF-tert dox-inducible amiRNA1 Mock, +PAA, 8 hpi, Mock, 5ug/ml dox for 24 h, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA1); time post_infection:Mock, +PAA, 8 hpi; infection:Mock; treatment:5ug/ml doxycycline for 24 h, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) Mock_plus_dox_rep1;SSRP1 KD GSM6336829 HFF-tert dox-inducible amiRNA2 Mock, +PAA, 8 hpi, Mock, 5ug/ml dox for 24 h, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA2); time post_infection:Mock, +PAA, 8 hpi; infection:Mock; treatment:5ug/ml doxycycline for 24 h, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) Mock_plus_dox_rep2;SSRP1 KD GSM6336803 HFF-tert, doxycycline-inducible ICP22, 5ug/ml doxycycline for 24h, 200mM KCl for 2h, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; treatment:5ug/ml doxycycline for 24h, 200mM KCl for 2h ICP22_dox_KCl_R2 GSM6336804 HFF-tert, doxycycline-inducible ICP22, 5ug/ml doxycycline for 24h, no KCl, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; treatment:5ug/ml doxycycline for 24h, no KCl ICP22_dox_R1 GSM5608558 T-HF cells, with no SPT6 KD, infected with ICP22-null mutant, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM6336830 HFF-tert dox-inducible amiRNA1 8 hpi, +PAA, HSV-1, strain F, no dox, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA1); time post_infection:8 hpi, +PAA; infection:HSV-1, strain F; treatment:no doxycycline, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) Wt_minus_dox_rep1;SSRP1 KD GSM6336805 HFF-tert, doxycycline-inducible ICP22, 5ug/ml doxycycline for 24h, no KCl, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; treatment:5ug/ml doxycycline for 24h, no KCl ICP22_dox_R2 GSM5608559 T-HF cells, with no SPT6 KD, infected with ICP22-null mutant, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM6336831 HFF-tert dox-inducible amiRNA2 8 hpi, +PAA, HSV-1, strain F, no dox, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA2); time post_infection:8 hpi, +PAA; infection:HSV-1, strain F; treatment:no doxycycline, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) Wt_minus_dox_rep2;SSRP1 KD GSM5608560 T-HF cells, with SPT6 KD, infected with ICP22-null mutant, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608561 T-HF cells, with SPT6 KD, infected with ICP22-null mutant, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608562 T-HF cells, with no SPT6 KD, mock, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:no infection; treatment:PAA (350 microg/ml); agent:no infection DNA isolated with Zymo DNA Clean & Concentrator GSM5608563 T-HF cells, with no SPT6 KD, mock, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:no infection; treatment:PAA (350 microg/ml); agent:no infection DNA isolated with Zymo DNA Clean & Concentrator GSM6336832 HFF-tert dox-inducible amiRNA1 8 hpi, +PAA, HSV-1, strain F, 5ug/ml dox for 24 h, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA1); time post_infection:8 hpi, +PAA; infection:HSV-1, strain F; treatment:5ug/ml doxycycline for 24 h, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) Wt_plus_dox_rep1;SSRP1 KD GSM6336806 HFF-tert, doxycycline-inducible ICP22, no doxycycline, 200mM KCl for 2h, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; treatment:no doxycycline, 200mM KCl for 2h ICP22_no_dox_KCl_R1 GSM5608564 T-HF cells, with SPT6 KD, mock, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:no infection; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:no infection DNA isolated with Zymo DNA Clean & Concentrator GSM6336833 HFF-tert dox-inducible amiRNA2 8 hpi, +PAA, HSV-1, strain F, 5ug/ml dox for 24 h, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA2); time post_infection:8 hpi, +PAA; infection:HSV-1, strain F; treatment:5ug/ml doxycycline for 24 h, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) Wt_plus_dox_rep2;SSRP1 KD GSM6336807 HFF-tert, doxycycline-inducible ICP22, no doxycycline, 200mM KCl for 2h, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; treatment:no doxycycline, 200mM KCl for 2h ICP22_no_dox_KCl_R2 GSM6336808 HFF-tert, doxycycline-inducible ICP22, no doxycycline, no KCl, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; treatment:no doxycycline, no KCl ICP22_no_dox_R1 GSM5608565 T-HF cells, with SPT6 KD, mock, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:no infection; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:no infection DNA isolated with Zymo DNA Clean & Concentrator GSM6336834 HFF-tert dox-inducible amiRNA1 8 hpi, +PAA, HSV-1, strain F, US1 deleted, no dox, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA1); time post_infection:8 hpi, +PAA; infection:HSV-1, strain F, US1 deleted; treatment:no doxycycline, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) ICP22_minus_dox_rep1;SSRP1 KD GSM5608566 T-HF cells, with no SPT6 KD, infected with WT strain F, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml); agent:Herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM6336809 HFF-tert, doxycycline-inducible ICP22, no doxycycline, no KCl, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP22 cassette and rtTA3; treatment:no doxycycline, no KCl ICP22_no_dox_R2 GSM6336835 HFF-tert dox-inducible amiRNA2 8 hpi, +PAA, HSV-1, strain F, US1 deleted, no dox, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA2); time post_infection:8 hpi, +PAA; infection:HSV-1, strain F, US1 deleted; treatment:no doxycycline, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) ICP22_minus_dox_rep2;SSRP1 KD GSM6336810 HFF-tert, doxycycline-inducible ICP27, 5ug/ml doxycycline for 24h, no KCl, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP27 cassette and rtTA3; treatment:5ug/ml doxycycline for 24h, no KCl ICP27_dox_R1 GSM6336836 HFF-tert dox-inducible amiRNA1 8 hpi, +PAA, HSV-1, strain F, US1 deleted, 5ug/ml dox for 24 h, rep1 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA1); time post_infection:8 hpi, +PAA; infection:HSV-1, strain F, US1 deleted; treatment:5ug/ml doxycycline for 24 h, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) ICP22_plus_dox_rep1;SSRP1 KD GSM6336811 HFF-tert, doxycycline-inducible ICP27, 5ug/ml doxycycline for 24h, no KCl, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible ICP27 cassette and rtTA3; treatment:5ug/ml doxycycline for 24h, no KCl ICP27_dox_R2 GSM6336837 HFF-tert dox-inducible amiRNA2 8 hpi, +PAA, HSV-1, strain F, US1 deleted, 5ug/ml dox for 24 h, rep2 tissue:foreskin; cell line:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; transduction:lentivirus containing an inducible artificial miRNA against SSRP1 (amiRNA2); time post_infection:8 hpi, +PAA; infection:HSV-1, strain F, US1 deleted; treatment:5ug/ml doxycycline for 24 h, 350 ug/ml PAA supplemented upon removal of inoculum (8h treatment) ICP22_plus_dox_rep2;SSRP1 KD GSM5608567 T-HF cells, with no SPT6 KD, infected with WT strain F, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml); agent:Herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608568 T-HF cells, with SPT6 KD, infected with WT strain F, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:Herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608569 T-HF cells, with SPT6 KD, infected with WT strain F, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:Herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608570 T-HF cells, with no SSRP1 KD, infected with ICP22-null mutant, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608571 T-HF cells, with no SSRP1 KD, infected with ICP22-null mutant, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608572 T-HF cells, with SSRP1 KD, infected with ICP22-null mutant, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608573 T-HF cells, with SSRP1 KD, infected with ICP22-null mutant, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:8 hpi; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:ICP22-null mutant of herpes simplex virus 1, strain F DNA isolated with Zymo DNA Clean & Concentrator GSM5608574 T-HF cells, with no SSRP1 KD, mock, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:no infection; treatment:PAA (350 microg/ml); agent:no infection DNA isolated with Zymo DNA Clean & Concentrator GSM5608575 T-HF cells, with no SSRP1 KD, mock, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:no infection; treatment:PAA (350 microg/ml); agent:no infection DNA isolated with Zymo DNA Clean & Concentrator GSM5608576 T-HF cells, with SSP1 KD, mock, replicate 1 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:no infection; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:no infection DNA isolated with Zymo DNA Clean & Concentrator GSM5608577 T-HF cells, with SSRP1 KD, mock, replicate 2 cell type:Human telomerase reverse transcriptase (hTERT)-Immortalized cell line; time post infection:no infection; treatment:PAA (350 microg/ml) + DOX (1 microg/mL); agent:no infection DNA isolated with Zymo DNA Clean & Concentrator
Platform	GPL18573  GPL28038  : Illumina NextSeq 500 (Homo sapiens);DNBSEQ-G400 (Homo sapiens)
Literature	37524699  40130876
Download	Download Genome Binding/Occupancy Profiling Analysis Data