Accession	GSE253562
Status	2024/10/15
Title	DNA methylation profiling of lung transplant recipients
Organism	Homo sapiens
Experiment type	Methylation profiling by high throughput sequencing
Summary	Targeted bisulfite sequencing data of peripheral blood mononuclear cells (PBMCs) from participants pre- and post- lung transplant(Tx) was generated to study 1) methylation difference between pre- and postTx, 2) methylation difference between cytomegalovirus (CMV) seropositive and seronegative in preTx, and 3) immune response regarding Tx and immunosuppression prophylaxes.
Samples	GSM ID Sample info Characteristics Description GSM8023292 130010 tissue:Blood; cell type:PBMC; age:68.09; Sex:M; ethnicity:Black; cmv r:POS; cmv d:POS; time:PreTx - GSM8023293 130021 tissue:Blood; cell type:PBMC; age:55.1; Sex:M; ethnicity:White; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023294 130029 tissue:Blood; cell type:PBMC; age:60.61; Sex:M; ethnicity:White; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023295 130034 tissue:Blood; cell type:PBMC; age:57.53; Sex:F; ethnicity:White; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023296 130059 tissue:Blood; cell type:PBMC; age:67.33; Sex:M; ethnicity:White; cmv r:POS; cmv d:UNK; time:PreTx - GSM8023297 130075 tissue:Blood; cell type:PBMC; age:34.18; Sex:F; ethnicity:Asian; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023333 140426 tissue:Blood; cell type:PBMC; age:64.16; Sex:F; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023298 130078 tissue:Blood; cell type:PBMC; age:65.69; Sex:F; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023334 140427 tissue:Blood; cell type:PBMC; age:65.22; Sex:M; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023335 140430-2 tissue:Blood; cell type:PBMC; age:63.44; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PostTx - GSM8023336 140430 tissue:Blood; cell type:PBMC; age:63.44; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023299 130086 tissue:Blood; cell type:PBMC; age:66.55; Sex:M; ethnicity:White; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023337 140460 tissue:Blood; cell type:PBMC; age:53.29; Sex:F; ethnicity:Hispanic; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023300 130093 tissue:Blood; cell type:PBMC; age:59.59; Sex:F; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023338 140468 tissue:Blood; cell type:PBMC; age:64.42; Sex:F; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023301 130103 tissue:Blood; cell type:PBMC; age:60.81; Sex:M; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023339 160013 tissue:Blood; cell type:PBMC; age:68.29; Sex:M; ethnicity:White; cmv r:NEG; cmv d:UNK; time:PreTx - GSM8023302 130116 tissue:Blood; cell type:PBMC; age:36.16; Sex:F; ethnicity:Hispanic; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023340 160014 tissue:Blood; cell type:PBMC; age:64.67; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023347 160048 tissue:Blood; cell type:PBMC; age:55.81; Sex:M; ethnicity:White; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023341 160020 tissue:Blood; cell type:PBMC; age:42.63; Sex:F; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023348 160058-2 tissue:Blood; cell type:PBMC; age:41.15; Sex:F; ethnicity:Hispanic; cmv r:NEG; cmv d:POS; time:PostTx - GSM8023342 160036-2 tissue:Blood; cell type:PBMC; age:66.49; Sex:M; ethnicity:White; cmv r:NEG; cmv d:POS; time:PostTx - GSM8023303 130135 tissue:Blood; cell type:PBMC; age:67.91; Sex:M; ethnicity:Hispanic; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023343 160036 tissue:Blood; cell type:PBMC; age:66.49; Sex:M; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023349 160058 tissue:Blood; cell type:PBMC; age:41.15; Sex:F; ethnicity:Hispanic; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023344 160043 tissue:Blood; cell type:PBMC; age:65.97; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023304 130138 tissue:Blood; cell type:PBMC; age:69.22; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023345 160044 tissue:Blood; cell type:PBMC; age:58.49; Sex:F; ethnicity:Black; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023350 160068-2 tissue:Blood; cell type:PBMC; age:69.66; Sex:M; ethnicity:White; cmv r:POS; cmv d:UNK; time:PostTx - GSM8023346 160048-2 tissue:Blood; cell type:PBMC; age:55.81; Sex:M; ethnicity:White; cmv r:POS; cmv d:NEG; time:PostTx - GSM8023351 160068 tissue:Blood; cell type:PBMC; age:69.66; Sex:M; ethnicity:White; cmv r:POS; cmv d:UNK; time:PreTx - GSM8023305 130176 tissue:Blood; cell type:PBMC; age:63.01; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023352 160080 tissue:Blood; cell type:PBMC; age:71.59; Sex:M; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023306 130178 tissue:Blood; cell type:PBMC; age:56.8; Sex:F; ethnicity:White; cmv r:POS; cmv d:UNK; time:PreTx - GSM8023353 170055 tissue:Blood; cell type:PBMC; age:67.73; Sex:F; ethnicity:White; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023354 170058 tissue:Blood; cell type:PBMC; age:63.93; Sex:M; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023307 130207 tissue:Blood; cell type:PBMC; age:59.89; Sex:M; ethnicity:White; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023355 170060 tissue:Blood; cell type:PBMC; age:67.15; Sex:M; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023356 170061 tissue:Blood; cell type:PBMC; age:67.54; Sex:F; ethnicity:White; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023308 130217 tissue:Blood; cell type:PBMC; age:64.82; Sex:M; ethnicity:Hispanic; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023357 180009 tissue:Blood; cell type:PBMC; age:65.68; Sex:M; ethnicity:Hispanic; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023358 180013 tissue:Blood; cell type:PBMC; age:66.44; Sex:F; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023309 130220 tissue:Blood; cell type:PBMC; age:57.85; Sex:F; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023359 180018 tissue:Blood; cell type:PBMC; age:58.88; Sex:M; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023310 130238 tissue:Blood; cell type:PBMC; age:67.43; Sex:F; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023360 180019-2 tissue:Blood; cell type:PBMC; age:63.01; Sex:F; ethnicity:Hispanic; cmv r:NEG; cmv d:POS; time:PostTx - GSM8023361 180019 tissue:Blood; cell type:PBMC; age:63.01; Sex:F; ethnicity:Hispanic; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023311 130239 tissue:Blood; cell type:PBMC; age:66.98; Sex:M; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023362 180030 tissue:Blood; cell type:PBMC; age:55.05; Sex:F; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023312 130246 tissue:Blood; cell type:PBMC; age:59.98; Sex:F; ethnicity:Black; cmv r:POS; cmv d:POS; time:PreTx - GSM8023363 180032 tissue:Blood; cell type:PBMC; age:58.64; Sex:M; ethnicity:White; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023364 180034 tissue:Blood; cell type:PBMC; age:68.13; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023313 130262 tissue:Blood; cell type:PBMC; age:68.29; Sex:F; ethnicity:White; cmv r:UNK; cmv d:UNK; time:PreTx - GSM8023365 180037 tissue:Blood; cell type:PBMC; age:68.94; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023314 140270 tissue:Blood; cell type:PBMC; age:44.41; Sex:M; ethnicity:Black; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023366 180052 tissue:Blood; cell type:PBMC; age:56.11; Sex:F; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023367 180056 tissue:Blood; cell type:PBMC; age:67.27; Sex:M; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023315 140279 tissue:Blood; cell type:PBMC; age:67.48; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023368 180064 tissue:Blood; cell type:PBMC; age:61.21; Sex:M; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023369 180067 tissue:Blood; cell type:PBMC; age:63.93; Sex:F; ethnicity:White; cmv r:NEG; cmv d:UNK; time:PreTx - GSM8023316 140282 tissue:Blood; cell type:PBMC; age:64.71; Sex:M; ethnicity:White; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023370 180071 tissue:Blood; cell type:PBMC; age:20.36; Sex:F; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023317 140301 tissue:Blood; cell type:PBMC; age:70.19; Sex:M; ethnicity:White; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023371 180073 tissue:Blood; cell type:PBMC; age:68.77; Sex:F; ethnicity:White; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023372 180077 tissue:Blood; cell type:PBMC; age:57.98; Sex:F; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023318 140302 tissue:Blood; cell type:PBMC; age:48.7; Sex:M; ethnicity:White; cmv r:POS; cmv d:UNK; time:PreTx - GSM8023373 190009 tissue:Blood; cell type:PBMC; age:72.27; Sex:M; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023374 190013 tissue:Blood; cell type:PBMC; age:67.13; Sex:M; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023319 140304 tissue:Blood; cell type:PBMC; age:62.55; Sex:M; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023375 190014 tissue:Blood; cell type:PBMC; age:69.89; Sex:F; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023320 140307-2 tissue:Blood; cell type:PBMC; age:64.22; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PostTx - GSM8023376 190020 tissue:Blood; cell type:PBMC; age:62.93; Sex:F; ethnicity:Other; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023377 190034 tissue:Blood; cell type:PBMC; age:63.71; Sex:M; ethnicity:White; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023321 140307 tissue:Blood; cell type:PBMC; age:64.22; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023378 190050 tissue:Blood; cell type:PBMC; age:68.44; Sex:F; ethnicity:Asian; cmv r:POS; cmv d:POS; time:PreTx - GSM8023379 190067 tissue:Blood; cell type:PBMC; age:69.13; Sex:F; ethnicity:White; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023322 140316 tissue:Blood; cell type:PBMC; age:59.67; Sex:M; ethnicity:Hispanic; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023380 190071 tissue:Blood; cell type:PBMC; age:43.46; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023323 140330 tissue:Blood; cell type:PBMC; age:62.99; Sex:F; ethnicity:Black; cmv r:POS; cmv d:UNK; time:PreTx - GSM8023381 190098 tissue:Blood; cell type:PBMC; age:63.38; Sex:M; ethnicity:Asian; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023382 200006 tissue:Blood; cell type:PBMC; age:64.22; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023324 140331 tissue:Blood; cell type:PBMC; age:61.57; Sex:F; ethnicity:White; cmv r:POS; cmv d:POS; time:PreTx - GSM8023383 200029 tissue:Blood; cell type:PBMC; age:35.09; Sex:F; ethnicity:Black; cmv r:NEG; cmv d:POS; time:PreTx - GSM8023325 140333 tissue:Blood; cell type:PBMC; age:69.39; Sex:M; ethnicity:Other; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023326 140335 tissue:Blood; cell type:PBMC; age:62.88; Sex:F; ethnicity:Asian; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023327 140351 tissue:Blood; cell type:PBMC; age:61.15; Sex:F; ethnicity:White; cmv r:POS; cmv d:NEG; time:PreTx - GSM8023328 140361 tissue:Blood; cell type:PBMC; age:66.9; Sex:F; ethnicity:White; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023329 140375 tissue:Blood; cell type:PBMC; age:24.92; Sex:F; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023330 140380 tissue:Blood; cell type:PBMC; age:70.95; Sex:F; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx - GSM8023331 140387 tissue:Blood; cell type:PBMC; age:55.19; Sex:F; ethnicity:White; cmv r:NEG; cmv d:NEG; time:PreTx - GSM8023332 140394 tissue:Blood; cell type:PBMC; age:45.89; Sex:F; ethnicity:Hispanic; cmv r:POS; cmv d:POS; time:PreTx -
Platform	GPL24676  : Illumina NovaSeq 6000 (Homo sapiens)
Literature	39360678
Download	Download Methylation Analysis Data