Virus Dataset Detail

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Dataset Information
Accession GSE64877
Status 2016/6/22
Title Global re-wiring of p53 transcription regulation by the hepatitis B virus X (HBx) protein [ChIP-Seq]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary As HBx has been reported to interact with p53 and alter the recruitment of p53 to its binding sites, we obtained a comprehensive genome-wide profile of deregulated p53 transcription complex-DNA binding by the HBx protein using massively parallel deep sequencing coupled to p53 chromatin immunoprecipitation (ChIP-Seq) on HBx-expressing and control HepG2 liver cell culture model system.
Samples
GSM ID Sample info Characteristics Description
GSM1581947 HepG2 treated detection of p53 binding sites cell line:HepG2; transduction:HBV HBx protein expressing; antibody:p53 FL-393 antibody; antibody vendor:Santa Cruz Biotechnology; antibody catalog number:sc-6243 -
GSM1581946 HepG2 control detection of p53 binding sites cell line:HepG2; transduction:Control; antibody:p53 FL-393 antibody; antibody vendor:Santa Cruz Biotechnology; antibody catalog number:sc-6243 -
Platform GPL9052  : Illumina Genome Analyzer (Homo sapiens)
Literature 27302019  
Download Download Genome Binding/Occupancy Profiling Analysis Data