Accession	GSE71450
Status	2016/5/6
Title	Genome-wide epigenetic alteration in adult T-cell leukemia cells and HTLV-1-mediated immortalized cells
Organism	Homo sapiens
Experiment type	Genome binding/occupancy profiling by genome tiling array
Summary	We performed ChIP-on-chip analysis of primary ATL patient cells, normal CD4+ T cells, and Tax-transduced cells to decipher the ATL-specific ‘epigenetic-code’ that was critical in ATL pathogenesis.
Samples	GSM ID Sample info Characteristics Description GSM1834876 Normal#1 H3K27me3 cell type:Normal CD4 T-cells isolated from PBMCs - GSM1834876 Normal#1 H3K27me3 cell type:Normal CD4 T-cells isolated from PBMCs - GSM1834877 Normal#2 H3K27me3 cell type:Normal CD4 T-cells isolated from PBMCs - GSM1834877 Normal#2 H3K27me3 cell type:Normal CD4 T-cells isolated from PBMCs - GSM1834878 ATL#1 H3K27me3 cell type:primary PBMCs from ATL patient - GSM1834878 ATL#1 H3K27me3 cell type:primary PBMCs from ATL patient - GSM1834879 ATL#2 H3K27me3 cell type:primary PBMCs from ATL patient - GSM1834879 ATL#2 H3K27me3 cell type:primary PBMCs from ATL patient - GSM1834880 ATL#3 H3K27me3 cell type:primary PBMCs from ATL patient - GSM1834880 ATL#3 H3K27me3 cell type:primary PBMCs from ATL patient - GSM1834881 Normal#1 H3K4me3 cell type:Normal CD4 T-cells isolated from PBMCs - GSM1834881 Normal#1 H3K4me3 cell type:Normal CD4 T-cells isolated from PBMCs - GSM1834882 ATL#1 H3K4me3 cell type:primary PBMCs from ATL patient - GSM1834882 ATL#1 H3K4me3 cell type:primary PBMCs from ATL patient - GSM1834883 ATL#2 H3K4me3 cell type:primary PBMCs from ATL patient - GSM1834883 ATL#2 H3K4me3 cell type:primary PBMCs from ATL patient - GSM1834884 ATL#3 H3K4me3 cell type:primary PBMCs from ATL patient - GSM1834884 ATL#3 H3K4me3 cell type:primary PBMCs from ATL patient - GSM1834885 Tax-cell H3K27me3 cell type:Tax transduced T-cells - GSM1834885 Tax-cell H3K27me3 cell type:Tax transduced T-cells - GSM1834886 Activated T-cell H3K27me3 cell type:CD3/CD28 activated CD4 T-cells - GSM1834886 Activated T-cell H3K27me3 cell type:CD3/CD28 activated CD4 T-cells - GSM1834887 TL-Om1 H3K27me3 cell type:TL-Om1 (ATL cell line) - GSM1834887 TL-Om1 H3K27me3 cell type:TL-Om1 (ATL cell line) - GSM1834888 TL-Om1 H3K4me3 cell type:TL-Om1 (ATL cell line) - GSM1834888 TL-Om1 H3K4me3 cell type:TL-Om1 (ATL cell line) - GSM1834889 MT-2 H3K27me3 cell type:MT-2 (HTLV-1 infected cell line) - GSM1834889 MT-2 H3K27me3 cell type:MT-2 (HTLV-1 infected cell line) - GSM1834890 MT-2 EZH2 cell type:MT-2 (HTLV-1 infected cell line) - GSM1834890 MT-2 EZH2 cell type:MT-2 (HTLV-1 infected cell line) - GSM1834891 MT-2 Tax cell type:MT-2 (HTLV-1 infected cell line) - GSM1834891 MT-2 Tax cell type:MT-2 (HTLV-1 infected cell line) - GSM1834892 MT-2 Control IgG cell type:MT-2 (HTLV-1 infected cell line) - GSM1834892 MT-2 Control IgG cell type:MT-2 (HTLV-1 infected cell line) -
Platform	GPL19784  : Agilent-027954 SurePrint G3 Human Promoter Microarray 2x400K [Probe Name version]
Literature	26773042