HIV Target gene Detail Information

> MSH3 Gene Search Result


Gene Information
Gene Name MSH3
Gene ID 4437
Gene Full Name mutS homolog 3
Gene Alias DUP|FAP4|MRP1
Transcripts ENSG00000113318
Virus HIV
Gene Type protein-coding
HPA Location Info Nuclear bodies;
Membrane Info Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P20585
HGNC ID HGNC:7326
OMIM ID 600887
Summary The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]
Target gene [MSH3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4007683 chr5 15 1 2 18 View
4009585 chr5 10 1 0 11 View
4010976 chr5 3 5 0 8 View
4011264 chr5 6 1 0 7 View
4011775 chr5 5 1 0 6 View
4015822 chr5 1 0 0 1 View
4016372 chr5 0 0 0 0 View

Target gene [MSH3] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
GSE144332 RNA-seq 75 NextSeq 550 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
C
  GSE30738 		Chip-seq 2 Illumina Genome Analyzer II (Homo sapiens)
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE221688 - MSH3 peak across samples

Peak Plot

> Dataset: GSE165705 - MSH3 peak across samples

Peak Plot

> Dataset: GSE30738 - MSH3 peak across samples

Peak Plot

> Dataset: GSE144329 - MSH3 peak across samples

Peak Plot

> Dataset: GSE220859 - MSH3 peak across samples

Peak Plot

> Dataset: GSE211651 - MSH3 peak across samples

Peak Plot

> Dataset: GSE100376 - MSH3 peak across samples

Peak Plot

> Dataset: GSE100266 - MSH3 peak across samples

Peak Plot

> Dataset: GSE165703 - MSH3 peak across samples

Peak Plot