HIV Target gene Detail Information

> NPLOC4 Gene Search Result


Gene Information
Gene Name NPLOC4
Gene ID 55666
Gene Full Name NPL4 homolog, ubiquitin recognition factor
Gene Alias NPL4
Transcripts ENSG00000182446
Virus HIV
Gene Type protein-coding
HPA Location Info Nucleoplasm, Cytosol;
Membrane Info Predicted intracellular proteins, Transporters
Uniport_ID Q8TAT6
HGNC ID HGNC:18261
OMIM ID 606590
Summary Predicted to enable ubiquitin binding activity and ubiquitin protein ligase binding activity. Predicted to contribute to K48-linked polyubiquitin modification-dependent protein binding activity and K63-linked polyubiquitin modification-dependent protein binding activity. Involved in negative regulation of RIG-I signaling pathway; negative regulation of type I interferon production; and proteolysis involved in protein catabolic process. Located in nucleus. Part of UFD1-NPL4 complex and VCP-NPL4-UFD1 AAA ATPase complex. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [NPLOC4] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000317 chr17 486 43 21 550 View
4000791 chr17 273 7 0 280 View
4002938 chr17 72 2 0 74 View
4002939 chr17 72 2 0 74 View
4003286 chr17 58 5 1 64 View
4003807 chr17 25 29 0 54 View
4004707 chr17 33 7 0 40 View
4006309 chr17 19 2 4 25 View
4006876 chr17 19 3 0 22 View
4007878 chr17 16 1 0 17 View
4011135 chr17 4 3 0 7 View
4011220 chr17 4 3 0 7 View

Target gene [NPLOC4] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
GSE144332 RNA-seq 75 NextSeq 550 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE198339 scRNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE221688 - NPLOC4 peak across samples

Peak Plot

> Dataset: GSE165705 - NPLOC4 peak across samples

Peak Plot

> Dataset: GSE144329 - NPLOC4 peak across samples

Peak Plot

> Dataset: GSE220859 - NPLOC4 peak across samples

Peak Plot

> Dataset: GSE211651 - NPLOC4 peak across samples

Peak Plot

> Dataset: GSE100376 - NPLOC4 peak across samples

Peak Plot

> Dataset: GSE100266 - NPLOC4 peak across samples

Peak Plot

> Dataset: GSE165703 - NPLOC4 peak across samples

Peak Plot