Gene Name	MARK2
Gene ID	2011
Gene Full Name	microtubule affinity regulating kinase 2
Gene Alias	EMK-1|EMK1|PAR-1|Par-1b|Par1b
Transcripts	ENSG00000072518
Virus	HIV
Gene Type	protein-coding
HPA Location Info	Plasma membrane;Nucleoplasm;
Membrane Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q7KZI7
HGNC ID	HGNC:3332
OMIM ID	600526
Summary	This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000223	chr11	352	253	94	699	View
4000401	chr11	32	260	199	491	View
4002174	chr11	76	7	25	108	View
4002809	chr11	79	0	0	79	View
4003578	chr11	31	25	2	58	View
4004514	chr11	32	2	9	43	View
4005450	chr11	31	0	1	32	View
4005688	chr11	30	0	0	30	View
4005732	chr11	5	12	13	30	View
4007395	chr11	7	2	10	19	View
4009518	chr11	10	1	0	11	View
4009642	chr11	3	5	3	11	View
4010173	chr11	8	1	0	9	View
4015736	chr11	0	1	0	1	View

Data ID	Experiment type	Sample number	Platform
C   GSE221688	Chip-seq;scATAC-Seq;scRNA-Seq	12	Illumina NovaSeq 6000 (Homo sapiens)
GSE99737	RNA-seq	9	Illumina HiSeq 2500 (Homo sapiens)
GSE144332	RNA-seq	75	NextSeq 550 (Homo sapiens)
C   GSE165705	Chip-seq	30	Illumina NovaSeq 6000 (Homo sapiens)
GSE164264	RNA-seq	6	BGISEQ-500 (Homo sapiens)
GSE262621	RNA-seq	70	Illumina NovaSeq 6000 (Homo sapiens)
GSE128121	RNA-seq	16	Illumina HiSeq 4000 (Homo sapiens)
GSE162914	RNA-seq	211	Illumina HiSeq 2500 (Homo sapiens)
GSE279982	Methylation profiling (Array)	576	Infinium MethylationEPIC
C   GSE144329	ATAC-seq	96	NextSeq 550 (Homo sapiens)
GSE205204	RNA-seq	14	Illumina NovaSeq 6000 (Homo sapiens)
GSE125686	RNA-seq	62	Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE198339	scRNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE233747	scRNA-seq	40	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE220859	Chip-seq	11	Illumina NovaSeq 6000 (Homo sapiens)
GSE165708	RNA-seq	100	Illumina HiSeq 4000 (Homo sapiens)
C   GSE211651	Chip-seq;RNA-seq;PRO-seq	39	Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE68028	MeDIP-chip	1	NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C   GSE100376	ATAC-seq	24	Illumina NextSeq 500 (Homo sapiens)
GSE167211	RNA-seq	1	Illumina HiSeq 2000 (Homo sapiens)
GSE165132	RNA-seq	56	NextSeq 550 (Homo sapiens)
C   GSE100266	ATAC-seq;Chip-seq;RNA-seq	32	Illumina HiSeq 2500 (Homo sapiens)
C   GSE165703	ATAC-seq	82	Illumina HiSeq 4000 (Homo sapiens)
GSE246082	RNA-seq	6	Illumina HiSeq 4000 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE221688 - MARK2 peak across samples

Peak Plot

> Dataset: GSE165705 - MARK2 peak across samples

Peak Plot

> Dataset: GSE144329 - MARK2 peak across samples

Peak Plot

> Dataset: GSE220859 - MARK2 peak across samples

Peak Plot

> Dataset: GSE211651 - MARK2 peak across samples

Peak Plot

> Dataset: GSE100376 - MARK2 peak across samples

Peak Plot

> Dataset: GSE100266 - MARK2 peak across samples

Peak Plot

> Dataset: GSE165703 - MARK2 peak across samples

Peak Plot