HIV Target gene Detail Information

> PPP6R2 Gene Search Result


Gene Information
Gene Name PPP6R2
Gene ID 9701
Gene Full Name protein phosphatase 6 regulatory subunit 2
Gene Alias KIAA0685|PP6R2|SAP190|SAPS2
Transcripts ENSG00000100239
Virus HIV
Gene Type protein-coding
HPA Location Info Cytosol;Cytoplasmic bodies;
Membrane Info Plasma proteins, Predicted intracellular proteins
Uniport_ID O75170
HGNC ID HGNC:19253
OMIM ID 610877
Summary The protein encoded by this gene is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment. [provided by RefSeq, May 2017]
Target gene [PPP6R2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000334 chr22 381 77 71 529 View
4000493 chr22 340 18 69 427 View
4002625 chr22 81 3 2 86 View
4002896 chr22 3 1 72 76 View
4002928 chr22 4 0 71 75 View
4004102 chr22 8 12 29 49 View
4007207 chr22 20 0 0 20 View
4007354 chr22 18 2 0 20 View
4009253 chr22 8 1 3 12 View
4010215 chr22 6 3 0 9 View
4010427 chr22 8 0 1 9 View
4011244 chr22 7 0 0 7 View
4011390 chr22 7 0 0 7 View
4011391 chr22 7 0 0 7 View
4011392 chr22 5 2 0 7 View
4011656 chr22 4 2 0 6 View
4011749 chr22 6 0 0 6 View
4012814 chr22 3 1 0 4 View
4013387 chr22 3 0 0 3 View
4013478 chr22 3 0 0 3 View
4013680 chr22 2 1 0 3 View
4013681 chr22 3 0 0 3 View
4013809 chr22 3 0 0 3 View
4013810 chr22 3 0 0 3 View
4014452 chr22 1 1 0 2 View
4014453 chr22 0 2 0 2 View
4015666 chr22 0 1 0 1 View
4016639 chr22 0 0 0 0 View

Target gene [PPP6R2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
E
  GSE144332 		RNA-seq 75 NextSeq 550 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE187515 scRNA-seq 104 Illumina MiSeq (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
GSE228078 scRNA-seq 12 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE144332 - PPP6R2 expression across samples

Volcano Plot

Bar Plot