HIV Target gene Detail Information

> STAT5B Gene Search Result


Gene Information
Gene Name STAT5B
Gene ID 6777
Gene Full Name signal transducer and activator of transcription 5B
Gene Alias GHISID2|STAT5
Transcripts ENSG00000173757
Virus HIV
Gene Type protein-coding
HPA Location Info Cytosol;
Membrane Info Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID P51692
HGNC ID HGNC:11367
OMIM ID 604260
Summary The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
Target gene [STAT5B] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000047 chr17 158 773 713 1644 View
4000142 chr17 174 436 301 911 View
4000881 chr17 79 112 64 255 View
4001303 chr17 161 17 3 181 View
4001361 chr17 22 77 75 174 View
4001429 chr17 16 77 74 167 View
4001441 chr17 13 77 74 164 View
4001922 chr17 36 52 35 123 View
4001991 chr17 28 87 4 119 View
4002012 chr17 28 86 4 118 View
4002125 chr17 23 84 4 111 View
4002126 chr17 23 84 4 111 View
4002192 chr17 20 83 4 107 View
4002209 chr17 19 83 4 106 View
4002210 chr17 19 83 4 106 View
4002528 chr17 36 19 34 89 View
4002917 chr17 72 3 0 75 View
4003167 chr17 32 34 2 68 View
4003331 chr17 16 29 19 64 View
4003966 chr17 38 10 3 51 View
4004128 chr17 45 4 0 49 View
4004529 chr17 32 10 1 43 View
4004608 chr17 38 4 0 42 View
4004609 chr17 38 4 0 42 View
4005529 chr17 21 9 1 31 View
4006027 chr17 24 3 0 27 View
4006289 chr17 6 13 7 26 View
4007593 chr17 1 17 0 18 View
4007731 chr17 10 6 2 18 View
4008074 chr17 8 6 2 16 View
4009102 chr17 9 3 0 12 View
4009355 chr17 1 9 2 12 View
4009380 chr17 12 0 0 12 View
4010041 chr17 0 10 0 10 View
4010143 chr17 9 0 0 9 View
4010918 chr17 4 4 0 8 View
4010919 chr17 4 4 0 8 View
4010921 chr17 4 4 0 8 View
4010923 chr17 4 4 0 8 View
4010924 chr17 4 4 0 8 View
4010925 chr17 4 4 0 8 View
4010926 chr17 4 4 0 8 View
4010927 chr17 4 4 0 8 View
4010928 chr17 4 4 0 8 View
4010929 chr17 4 4 0 8 View
4010930 chr17 4 4 0 8 View
4010931 chr17 8 0 0 8 View
4010932 chr17 8 0 0 8 View
4011063 chr17 0 7 0 7 View
4011373 chr17 2 5 0 7 View
4011589 chr17 5 1 0 6 View
4011990 chr17 5 1 0 6 View
4013170 chr17 4 0 0 4 View
4013311 chr17 3 1 0 4 View
4014156 chr17 0 2 0 2 View
4014402 chr17 0 2 0 2 View
4014919 chr17 2 0 0 2 View
4015632 chr17 0 1 0 1 View
4015750 chr17 1 0 0 1 View
4016793 chr17 17 83 4 104 View
4016843 chr17 33 4 0 37 View

Target gene [STAT5B] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
GSE144332 RNA-seq 75 NextSeq 550 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
C
  GSE30738 		Chip-seq 2 Illumina Genome Analyzer II (Homo sapiens)
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE187515 scRNA-seq 104 Illumina MiSeq (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE198339 scRNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE221688 - STAT5B peak across samples

Peak Plot

> Dataset: GSE165705 - STAT5B peak across samples

Peak Plot

> Dataset: GSE30738 - STAT5B peak across samples

Peak Plot

> Dataset: GSE144329 - STAT5B peak across samples

Peak Plot

> Dataset: GSE220859 - STAT5B peak across samples

Peak Plot

> Dataset: GSE211651 - STAT5B peak across samples

Peak Plot

> Dataset: GSE100376 - STAT5B peak across samples

Peak Plot

> Dataset: GSE100266 - STAT5B peak across samples

Peak Plot

> Dataset: GSE165703 - STAT5B peak across samples

Peak Plot