Gene Name	DLG1
Gene ID	1739
Gene Full Name	discs large MAGUK scaffold protein 1
Gene Alias	DLGH1|SAP-97|SAP97|hdlg
Transcripts	ENSG00000075711
Virus	HIV
Gene Type	protein-coding
HPA Location Info	Vesicles;Plasma membrane, Basal body;
Membrane Info	Predicted intracellular proteins, Transporters
Uniport_ID	Q12959
HGNC ID	HGNC:2900
OMIM ID	601014
Summary	This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. A multitude of transcript variants deriving from alternative splicing and the use of multiple alternate promoter have been observed, including some splice variants that may be specific to brain and other tissues. An upstream uORF may regulate translation at some splice variants of this gene. [provided by RefSeq, Sep 2018]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003383	chr3	62	0	0	62	View
4004187	chr3	33	15	0	48	View
4005302	chr3	33	0	1	34	View
4005863	chr3	29	0	0	29	View
4005920	chr3	22	4	2	28	View
4006170	chr3	3	13	10	26	View
4006498	chr3	17	3	4	24	View
4008498	chr3	9	6	0	15	View
4010600	chr3	5	3	0	8	View
4011098	chr3	2	5	0	7	View
4011615	chr3	6	0	0	6	View
4011764	chr3	4	2	0	6	View
4014217	chr3	1	1	0	2	View
4015117	chr3	1	0	0	1	View
4016765	chr3	0	0	0	0	View
4016766	chr3	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
C   GSE221688	Chip-seq;scATAC-Seq;scRNA-Seq	12	Illumina NovaSeq 6000 (Homo sapiens)
GSE99737	RNA-seq	9	Illumina HiSeq 2500 (Homo sapiens)
GSE144332	RNA-seq	75	NextSeq 550 (Homo sapiens)
GSE157829	scRNA-seq	7	Illumina HiSeq 2500 (Homo sapiens)
C   GSE165705	Chip-seq	30	Illumina NovaSeq 6000 (Homo sapiens)
GSE164264	RNA-seq	6	BGISEQ-500 (Homo sapiens)
C   GSE30738	Chip-seq	2	Illumina Genome Analyzer II (Homo sapiens)
GSE262621	RNA-seq	70	Illumina NovaSeq 6000 (Homo sapiens)
GSE128121	RNA-seq	16	Illumina HiSeq 4000 (Homo sapiens)
GSE162914	RNA-seq	211	Illumina HiSeq 2500 (Homo sapiens)
GSE279982	Methylation profiling (Array)	576	Infinium MethylationEPIC
C   GSE144329	ATAC-seq	96	NextSeq 550 (Homo sapiens)
GSE205204	RNA-seq	14	Illumina NovaSeq 6000 (Homo sapiens)
GSE125686	RNA-seq	62	Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE198339	scRNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE220859	Chip-seq	11	Illumina NovaSeq 6000 (Homo sapiens)
GSE165708	RNA-seq	100	Illumina HiSeq 4000 (Homo sapiens)
C   GSE211651	Chip-seq;RNA-seq;PRO-seq	39	Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE68028	MeDIP-chip	1	NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C   GSE100376	ATAC-seq	24	Illumina NextSeq 500 (Homo sapiens)
GSE167211	RNA-seq	1	Illumina HiSeq 2000 (Homo sapiens)
GSE165132	RNA-seq	56	NextSeq 550 (Homo sapiens)
C   GSE100266	ATAC-seq;Chip-seq;RNA-seq	32	Illumina HiSeq 2500 (Homo sapiens)
C   GSE165703	ATAC-seq	82	Illumina HiSeq 4000 (Homo sapiens)
GSE246082	RNA-seq	6	Illumina HiSeq 4000 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE221688 - DLG1 peak across samples

Peak Plot

> Dataset: GSE165705 - DLG1 peak across samples

Peak Plot

> Dataset: GSE30738 - DLG1 peak across samples

Peak Plot

> Dataset: GSE144329 - DLG1 peak across samples

Peak Plot

> Dataset: GSE220859 - DLG1 peak across samples

Peak Plot

> Dataset: GSE211651 - DLG1 peak across samples

Peak Plot

> Dataset: GSE100376 - DLG1 peak across samples

Peak Plot

> Dataset: GSE100266 - DLG1 peak across samples

Peak Plot

> Dataset: GSE165703 - DLG1 peak across samples

Peak Plot