HIV Target gene Detail Information

> PACS1 Gene Search Result


Gene Information
Gene Name PACS1
Gene ID 55690
Gene Full Name phosphofurin acidic cluster sorting protein 1
Gene Alias MRD17|SHMS
Transcripts ENSG00000175115
Virus HIV
Gene Type protein-coding
HPA Location Info Plasma membrane;Vesicles;
Membrane Info Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q6VY07
HGNC ID HGNC:30032
OMIM ID 607492
Summary This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008]
Target gene [PACS1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000121 chr11 155 508 327 990 View
4000278 chr11 208 156 235 599 View
4000490 chr11 323 58 47 428 View
4001228 chr11 8 160 23 191 View
4001423 chr11 96 25 46 167 View
4001517 chr11 17 132 6 155 View
4001587 chr11 149 0 0 149 View
4001658 chr11 125 18 0 143 View
4002493 chr11 86 3 3 92 View
4002542 chr11 42 42 6 90 View
4002600 chr11 29 49 9 87 View
4003036 chr11 58 13 0 71 View
4003710 chr11 49 7 0 56 View
4003815 chr11 35 19 0 54 View
4003879 chr11 15 21 17 53 View
4004262 chr11 32 10 5 47 View
4004884 chr11 22 15 1 38 View
4004943 chr11 36 1 0 37 View
4005059 chr11 32 4 0 36 View
4005105 chr11 1 7 28 36 View
4005306 chr11 32 2 0 34 View
4005514 chr11 32 0 0 32 View
4005904 chr11 28 0 0 28 View
4006407 chr11 22 3 0 25 View
4006565 chr11 20 4 0 24 View
4006736 chr11 13 10 0 23 View
4006864 chr11 1 10 11 22 View
4007036 chr11 18 2 1 21 View
4007599 chr11 13 4 1 18 View
4007872 chr11 16 1 0 17 View
4008064 chr11 7 9 0 16 View
4008065 chr11 6 10 0 16 View
4008219 chr11 2 5 9 16 View
4008325 chr11 13 2 0 15 View
4008394 chr11 13 2 0 15 View
4008915 chr11 13 0 0 13 View
4009364 chr11 7 4 1 12 View
4009436 chr11 7 4 0 11 View
4009519 chr11 4 0 7 11 View
4009801 chr11 8 2 0 10 View
4010028 chr11 7 3 0 10 View
4010174 chr11 5 4 0 9 View
4010269 chr11 9 0 0 9 View
4010270 chr11 0 9 0 9 View
4010668 chr11 7 1 0 8 View
4010944 chr11 5 3 0 8 View
4011038 chr11 0 7 0 7 View
4011649 chr11 2 4 0 6 View
4011686 chr11 4 2 0 6 View
4011687 chr11 6 0 0 6 View
4012436 chr11 4 1 0 5 View
4012693 chr11 3 1 0 4 View
4014128 chr11 0 2 0 2 View
4014334 chr11 1 1 0 2 View
4014335 chr11 2 0 0 2 View
4014673 chr11 0 2 0 2 View
4015168 chr11 1 0 0 1 View
4015228 chr11 1 0 0 1 View
4015590 chr11 0 1 0 1 View
4015591 chr11 1 0 0 1 View
4015592 chr11 0 1 0 1 View
4015948 chr11 0 0 0 0 View
4016570 chr11 0 0 0 0 View

Target gene [PACS1] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
GSE144332 RNA-seq 75 NextSeq 550 (Homo sapiens)
GSE157829 scRNA-seq 7 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
C
  GSE30738 		Chip-seq 2 Illumina Genome Analyzer II (Homo sapiens)
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE187515 scRNA-seq 104 Illumina MiSeq (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
GSE228078 scRNA-seq 12 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE221688 - PACS1 peak across samples

Peak Plot

> Dataset: GSE165705 - PACS1 peak across samples

Peak Plot

> Dataset: GSE30738 - PACS1 peak across samples

Peak Plot

> Dataset: GSE144329 - PACS1 peak across samples

Peak Plot

> Dataset: GSE220859 - PACS1 peak across samples

Peak Plot

> Dataset: GSE211651 - PACS1 peak across samples

Peak Plot

> Dataset: GSE100376 - PACS1 peak across samples

Peak Plot

> Dataset: GSE100266 - PACS1 peak across samples

Peak Plot

> Dataset: GSE165703 - PACS1 peak across samples

Peak Plot