HIV Target gene Detail Information

> SMG6 Gene Search Result


Gene Information
Gene Name SMG6
Gene ID 23293
Gene Full Name SMG6 nonsense mediated mRNA decay factor
Gene Alias C17orf31|EST1A|SMG-6|hEST1A|hSMG5/7a
Transcripts ENSG00000070366
Virus HIV
Gene Type protein-coding
HPA Location Info Nucleoli;Plasma membrane, Basal body, Cytosol;
Membrane Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q86US8
HGNC ID HGNC:17809
OMIM ID 610963
Summary This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. [provided by RefSeq, Feb 2014]
Target gene [SMG6] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000085 chr17 838 213 136 1187 View
4000293 chr17 181 152 249 582 View
4000340 chr17 277 48 198 523 View
4000341 chr17 277 48 198 523 View
4000342 chr17 277 48 198 523 View
4000343 chr17 277 48 198 523 View
4000344 chr17 277 48 198 523 View
4000345 chr17 277 48 198 523 View
4000346 chr17 277 48 198 523 View
4000347 chr17 277 48 198 523 View
4000383 chr17 358 49 93 500 View
4000865 chr17 15 86 161 262 View
4001653 chr17 123 17 3 143 View
4003158 chr17 36 16 16 68 View
4003180 chr17 44 8 15 67 View
4004971 chr17 30 2 5 37 View
4005094 chr17 21 13 2 36 View
4005168 chr17 34 1 0 35 View
4005202 chr17 9 11 15 35 View
4005603 chr17 29 2 0 31 View
4006683 chr17 3 20 0 23 View
4006989 chr17 21 0 0 21 View
4007253 chr17 20 0 0 20 View
4007876 chr17 17 0 0 17 View
4007877 chr17 11 6 0 17 View
4008769 chr17 0 14 0 14 View
4009231 chr17 5 6 1 12 View
4010405 chr17 8 1 0 9 View
4011532 chr17 4 2 0 6 View
4012249 chr17 4 0 1 5 View
4012909 chr17 4 0 0 4 View
4015298 chr17 1 0 0 1 View
4015299 chr17 0 1 0 1 View

Target gene [SMG6] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
GSE144332 RNA-seq 75 NextSeq 550 (Homo sapiens)
GSE157829 scRNA-seq 7 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
C
  GSE30738 		Chip-seq 2 Illumina Genome Analyzer II (Homo sapiens)
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE187515 scRNA-seq 104 Illumina MiSeq (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE198339 scRNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE221688 - SMG6 peak across samples

Peak Plot

> Dataset: GSE165705 - SMG6 peak across samples

Peak Plot

> Dataset: GSE30738 - SMG6 peak across samples

Peak Plot

> Dataset: GSE144329 - SMG6 peak across samples

Peak Plot

> Dataset: GSE220859 - SMG6 peak across samples

Peak Plot

> Dataset: GSE211651 - SMG6 peak across samples

Peak Plot

> Dataset: GSE100376 - SMG6 peak across samples

Peak Plot

> Dataset: GSE100266 - SMG6 peak across samples

Peak Plot

> Dataset: GSE165703 - SMG6 peak across samples

Peak Plot