HIV Target gene Detail Information

> SPPL3 Gene Search Result


Gene Information
Gene Name SPPL3
Gene ID 121665
Gene Full Name signal peptide peptidase like 3
Gene Alias IMP2|MDHV1887|PRO4332|PSH1|PSL4
Transcripts ENSG00000157837
Virus HIV
Gene Type protein-coding
HPA Location Info Vesicles, Plasma membrane;
Membrane Info Enzymes, Predicted membrane proteins
Uniport_ID Q8TCT6
HGNC ID HGNC:30424
OMIM ID 608240
Summary Enables aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Involved in T cell receptor signaling pathway; membrane protein proteolysis; and positive regulation of calcineurin-NFAT signaling cascade. Located in Golgi-associated vesicle membrane; endoplasmic reticulum; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [SPPL3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000611 chr12 314 17 10 341 View
4002183 chr12 104 3 0 107 View
4003198 chr12 61 6 0 67 View
4003460 chr12 36 15 10 61 View
4003480 chr12 57 3 0 60 View
4004055 chr12 6 17 27 50 View
4005466 chr12 32 0 0 32 View
4005628 chr12 30 1 0 31 View
4005906 chr12 10 17 1 28 View
4006144 chr12 27 0 0 27 View
4007494 chr12 15 3 1 19 View
4008068 chr12 8 8 0 16 View
4008455 chr12 9 3 3 15 View
4011193 chr12 7 0 0 7 View
4011877 chr12 5 0 1 6 View
4012216 chr12 3 2 0 5 View
4014093 chr12 2 0 0 2 View
4015255 chr12 1 0 0 1 View

Target gene [SPPL3] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
GSE144332 RNA-seq 75 NextSeq 550 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
C
  GSE30738 		Chip-seq 2 Illumina Genome Analyzer II (Homo sapiens)
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE148796 scRNA-seq 4 Illumina NextSeq 500 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE221688 - SPPL3 peak across samples

Peak Plot

> Dataset: GSE165705 - SPPL3 peak across samples

Peak Plot

> Dataset: GSE30738 - SPPL3 peak across samples

Peak Plot

> Dataset: GSE144329 - SPPL3 peak across samples

Peak Plot

> Dataset: GSE220859 - SPPL3 peak across samples

Peak Plot

> Dataset: GSE211651 - SPPL3 peak across samples

Peak Plot

> Dataset: GSE100376 - SPPL3 peak across samples

Peak Plot

> Dataset: GSE100266 - SPPL3 peak across samples

Peak Plot

> Dataset: GSE165703 - SPPL3 peak across samples

Peak Plot