HIV Target gene Detail Information

> PPP2R5A Gene Search Result


Gene Information
Gene Name PPP2R5A
Gene ID 5525
Gene Full Name protein phosphatase 2 regulatory subunit B'alpha
Gene Alias B56A|B56alpha|PR61A
Transcripts ENSG00000066027
Virus HIV
Gene Type protein-coding
HPA Location Info Cytosol;
Membrane Info Predicted intracellular proteins
Uniport_ID Q15172
HGNC ID HGNC:9309
OMIM ID 601643
Summary The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Target gene [PPP2R5A] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 31665623 G33K
Vif
Vif
HIV Infections
G
R
S
T
 View
2 31665623 G33R
Vif
Vif
HIV Infections
G
R
S
T
 View
3 31665623 G75T
Vif
Vif
HIV Infections
G
R
S
T
 View
4 31665623 I31V
Vif
Vif
HIV Infections
G
R
S
T
 View
5 31665623 L72R
Vif
Vif
HIV Infections
G
R
S
T
 View
6 31665623 N140Y
Vif
Vif
HIV Infections
G
R
S
T
 View
7 31665623 Q105R
Vif
Vif
HIV Infections
G
R
S
T
 View
8 31665623 Q83H
Vif
Vif
HIV Infections
G
R
S
T
 View
9 31665623 R23A
Vif
Vif
HIV Infections
G
R
S
T
 View
10 31665623 V31I
Vif
Vif
HIV Infections
G
R
S
T
 View

Target gene [PPP2R5A] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
GSE144332 RNA-seq 75 NextSeq 550 (Homo sapiens)
GSE157829 scRNA-seq 7 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
C
  GSE30738 		Chip-seq 2 Illumina Genome Analyzer II (Homo sapiens)
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE198339 scRNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE198809 scRNA-seq 46 Illumina NovaSeq 6000 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE221688 - PPP2R5A peak across samples

Peak Plot

> Dataset: GSE165705 - PPP2R5A peak across samples

Peak Plot

> Dataset: GSE30738 - PPP2R5A peak across samples

Peak Plot

> Dataset: GSE144329 - PPP2R5A peak across samples

Peak Plot

> Dataset: GSE220859 - PPP2R5A peak across samples

Peak Plot

> Dataset: GSE211651 - PPP2R5A peak across samples

Peak Plot

> Dataset: GSE100376 - PPP2R5A peak across samples

Peak Plot

> Dataset: GSE100266 - PPP2R5A peak across samples

Peak Plot

> Dataset: GSE165703 - PPP2R5A peak across samples

Peak Plot