Gene Name	BST2
Gene ID	684
Gene Full Name	bone marrow stromal cell antigen 2
Gene Alias	CD317|HM1.24|TETHERIN
Transcripts	ENSG00000130303
Virus	HIV
Gene Type	protein-coding
HPA Location Info	Golgi apparatus, Vesicles;
Membrane Info	CD markers, Plasma proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q10589
HGNC ID	HGNC:1119
OMIM ID	600534
Summary	Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008]

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	24465210	A14L	Vpu	Vpu	HIV Infections	G R I C L T	View
2	24465210	A15T	Vpu	Vpu	HIV Infections	G R I C L T	View
3	24465210	A15V	Vpu	Vpu	HIV Infections	G R I C L T	View
4	24465210	A19E	Vpu	Vpu	HIV Infections	G R I C L T	View
5	24465210	A50T	Vpu	Vpu	HIV Infections	G R I C L T	View
6	24465210	A50V	Vpu	Vpu	HIV Infections	G R I C L T	View
7	24465210	D52V	Vpu	Vpu	HIV Infections	G R I C L T	View
8	24465210	E29K	Vpu	Vpu	HIV Infections	G R I C L T	View
9	24465210	E56G	Vpu	Vpu	HIV Infections	G R I C L T	View
10	24465210	E58K	Vpu	Vpu	HIV Infections	G R I C L T	View
11	24465210	E62G	Vpu	Vpu	HIV Infections	G R I C L T	View
12	24465210	G59R	Vpu	Vpu	HIV Infections	G R I C L T	View
13	24465210	I16E	Vpu	Vpu	HIV Infections	G R I C L T	View
14	24465210	I17T	Vpu	Vpu	HIV Infections	G R I C L T	View
15	24465210	I39L	Vpu	Vpu	HIV Infections	G R I C L T	View
16	24465210	I9M	Vpu	Vpu	HIV Infections	G R I C L T	View
17	24465210	N55H	Vpu	Vpu	HIV Infections	G R I C L T	View
18	24465210	S53N	Vpu	Vpu	HIV Infections	G R I C L T	View
19	24465210	V22A	Vpu	Vpu	HIV Infections	G R I C L T	View
20	21237475	A18F	Vpu	Vpu	Cell line	G R T	View
21	21237475	I17A	Vpu	Vpu	Cell line	G R T	View
22	21237475	S23L	Vpu	Vpu	Cell line	G R T	View
23	21237475	S52N	Vpu	Vpu	Cell line	G R T	View
24	21237475	S56N	Vpu	Vpu	Cell line	G R T	View
25	21237475	W22L	Vpu	Vpu	Cell line	G R T	View
26	30717826	A15L	Vpu	Vpu	HIV Infections	G R S L T	View
27	30717826	A19L	Vpu	Vpu	HIV Infections	G R S L T	View
28	30717826	A20L	Vpu	Vpu	HIV Infections	G R S L T	View
29	30717826	A24L	Vpu	Vpu	HIV Infections	G R S L T	View
30	31234536	A11F	Vpu	Vpu	HIV Infections	G S T	View
31	31234536	A11L	Vpu	Vpu	HIV Infections	G S T	View
32	31234536	A11T	Vpu	Vpu	HIV Infections	G S T	View
33	31234536	A15L	Vpu	Vpu	HIV Infections	G S T	View
34	31234536	A15T	Vpu	Vpu	HIV Infections	G S T	View
35	31234536	A19F	Vpu	Vpu	HIV Infections	G S T	View
36	31234536	A19H	Vpu	Vpu	HIV Infections	G S T	View
37	31234536	A19L	Vpu	Vpu	HIV Infections	G S T	View
38	31234536	A19T	Vpu	Vpu	HIV Infections	G S T	View
39	31234536	F44Y	Vpu	Vpu	HIV Infections	G S T	View
40	31234536	G25A	Vpu	Vpu	HIV Infections	G S T	View
41	31234536	I17A	Vpu	Vpu	HIV Infections	G S T	View
42	31234536	I18T	Vpu	Vpu	HIV Infections	G S T	View
43	31234536	I33T	Vpu	Vpu	HIV Infections	G S T	View
44	31234536	I34T	Vpu	Vpu	HIV Infections	G S T	View
45	31234536	I36G	Vpu	Vpu	HIV Infections	G S T	View
46	31234536	K32A	Vpu	Vpu	HIV Infections	G S T	View
47	31234536	L07S	Vpu	Vpu	HIV Infections	G S T	View
48	31234536	L22S	Vpu	Vpu	HIV Infections	G S T	View
49	31234536	L22Y	Vpu	Vpu	HIV Infections	G S T	View
50	31234536	L23T	Vpu	Vpu	HIV Infections	G S T	View
51	31234536	L23Y	Vpu	Vpu	HIV Infections	G S T	View
52	31234536	L24F	Vpu	Vpu	HIV Infections	G S T	View
53	31234536	L24M	Vpu	Vpu	HIV Infections	G S T	View
54	31234536	L24T	Vpu	Vpu	HIV Infections	G S T	View
55	31234536	L29Q	Vpu	Vpu	HIV Infections	G S T	View
56	31234536	L37I	Vpu	Vpu	HIV Infections	G S T	View
57	31234536	L37T	Vpu	Vpu	HIV Infections	G S T	View
58	31234536	L41Y	Vpu	Vpu	HIV Infections	G S T	View
59	31234536	P40T	Vpu	Vpu	HIV Infections	G S T	View
60	31234536	Q05V	Vpu	Vpu	HIV Infections	G S T	View
61	31234536	R31A	Vpu	Vpu	HIV Infections	G S T	View
62	31234536	S03Y	Vpu	Vpu	HIV Infections	G S T	View
63	31234536	T45I	Vpu	Vpu	HIV Infections	G S T	View
64	31234536	V10K	Vpu	Vpu	HIV Infections	G S T	View
65	31234536	V14K	Vpu	Vpu	HIV Infections	G S T	View
66	31234536	V14L	Vpu	Vpu	HIV Infections	G S T	View
67	31234536	V14T	Vpu	Vpu	HIV Infections	G S T	View
68	31234536	V30G	Vpu	Vpu	HIV Infections	G S T	View
69	31234536	W23K	Vpu	Vpu	HIV Infections	G S T	View
70	31234536	W23L	Vpu	Vpu	HIV Infections	G S T	View
71	31234536	W23Y	Vpu	Vpu	HIV Infections	G S T	View

Data ID	Experiment type	Sample number	Platform
C   GSE221688	Chip-seq;scATAC-Seq;scRNA-Seq	12	Illumina NovaSeq 6000 (Homo sapiens)
GSE99737	RNA-seq	9	Illumina HiSeq 2500 (Homo sapiens)
E   GSE144332	RNA-seq	75	NextSeq 550 (Homo sapiens)
GSE157829	scRNA-seq	7	Illumina HiSeq 2500 (Homo sapiens)
C   GSE165705	Chip-seq	30	Illumina NovaSeq 6000 (Homo sapiens)
GSE164264	RNA-seq	6	BGISEQ-500 (Homo sapiens)
GSE262621	RNA-seq	70	Illumina NovaSeq 6000 (Homo sapiens)
GSE202410	scRNA-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE128121	RNA-seq	16	Illumina HiSeq 4000 (Homo sapiens)
GSE162914	RNA-seq	211	Illumina HiSeq 2500 (Homo sapiens)
GSE187515	scRNA-seq	104	Illumina MiSeq (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE279982	Methylation profiling (Array)	576	Infinium MethylationEPIC
C   GSE144329	ATAC-seq	96	NextSeq 550 (Homo sapiens)
GSE205204	RNA-seq	14	Illumina NovaSeq 6000 (Homo sapiens)
GSE125686	RNA-seq	62	Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
S   GSE198339	scRNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE233747	scRNA-seq	40	Illumina NovaSeq 6000 (Homo sapiens)
GSE165708	RNA-seq	100	Illumina HiSeq 4000 (Homo sapiens)
GSE211651	Chip-seq;RNA-seq;PRO-seq	39	Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
S   GSE198809	scRNA-seq	46	Illumina NovaSeq 6000 (Homo sapiens)
GSE68028	MeDIP-chip	1	NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C   GSE100376	ATAC-seq	24	Illumina NextSeq 500 (Homo sapiens)
GSE167211	RNA-seq	1	Illumina HiSeq 2000 (Homo sapiens)
GSE165132	RNA-seq	56	NextSeq 550 (Homo sapiens)
S   GSE228078	scRNA-seq	12	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100266	ATAC-seq;Chip-seq;RNA-seq	32	Illumina HiSeq 2500 (Homo sapiens)
C   GSE165703	ATAC-seq	82	Illumina HiSeq 4000 (Homo sapiens)
S   GSE148796	scRNA-seq	4	Illumina NextSeq 500 (Homo sapiens)
E   GSE246082	RNA-seq	6	Illumina HiSeq 4000 (Homo sapiens)

• Expression profiling
• scRNA data
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: GSE144332 - BST2 expression across samples

Volcano Plot

Bar Plot

> Dataset: GSE246082 - BST2 expression across samples

Volcano Plot

Bar Plot