HIV Target gene Detail Information

> POLR2E Gene Search Result


Gene Information
Gene Name POLR2E
Gene ID 5434
Gene Full Name RNA polymerase II, I and III subunit E
Gene Alias RPABC1|RPB5|XAP4|hRPB25|hsRPB5
Transcripts ENSG00000099817
Virus HIV
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins
Uniport_ID P19388
HGNC ID HGNC:9192
OMIM ID 180664
Summary This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Target gene [POLR2E] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4005002 chr19 37 0 0 37 View
4007667 chr19 18 0 0 18 View
4008159 chr19 16 0 0 16 View

Target gene [POLR2E] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
E
  GSE144332 		RNA-seq 75 NextSeq 550 (Homo sapiens)
GSE157829 scRNA-seq 7 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE202410 scRNA-seq 24 Illumina HiSeq 4000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE187515 scRNA-seq 104 Illumina MiSeq (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE198339 scRNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE233747 scRNA-seq 40 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE198809 scRNA-seq 46 Illumina NovaSeq 6000 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
S
  GSE148796 		scRNA-seq 4 Illumina NextSeq 500 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE144332 - POLR2E expression across samples

Volcano Plot

Bar Plot