Gene Name	USP3
Gene ID	9960
Gene Full Name	ubiquitin specific peptidase 3
Gene Alias	SIH003|UBP
Transcripts	ENSG00000140455
Virus	HIV
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Midbody ring;Intracellular and membrane;
Membrane Info	Enzymes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID	Q9Y6I4
HGNC ID	HGNC:12626
OMIM ID	604728
Summary	Enables deubiquitinase activity and histone binding activity. Involved in DNA repair and DNA repair-dependent chromatin remodeling. Located in several cellular components, including Flemming body; cytoplasmic ribonucleoprotein granule; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000078	chr15	225	374	667	1266	View
4000219	chr15	442	106	158	706	View
4001323	chr15	17	56	105	178	View
4001797	chr15	121	7	3	131	View
4004463	chr15	40	4	0	44	View
4005037	chr15	29	5	2	36	View
4008002	chr15	16	0	1	17	View
4008601	chr15	8	6	0	14	View
4009443	chr15	11	0	0	11	View
4011049	chr15	4	3	0	7	View
4012456	chr15	0	5	0	5	View
4013160	chr15	1	3	0	4	View
4013861	chr15	1	2	0	3	View
4015910	chr15	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
C   GSE221688	Chip-seq;scATAC-Seq;scRNA-Seq	12	Illumina NovaSeq 6000 (Homo sapiens)
GSE99737	RNA-seq	9	Illumina HiSeq 2500 (Homo sapiens)
GSE144332	RNA-seq	75	NextSeq 550 (Homo sapiens)
GSE157829	scRNA-seq	7	Illumina HiSeq 2500 (Homo sapiens)
C   GSE165705	Chip-seq	30	Illumina NovaSeq 6000 (Homo sapiens)
GSE164264	RNA-seq	6	BGISEQ-500 (Homo sapiens)
C   GSE30738	Chip-seq	2	Illumina Genome Analyzer II (Homo sapiens)
GSE262621	RNA-seq	70	Illumina NovaSeq 6000 (Homo sapiens)
GSE202410	scRNA-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE128121	RNA-seq	16	Illumina HiSeq 4000 (Homo sapiens)
GSE162914	RNA-seq	211	Illumina HiSeq 2500 (Homo sapiens)
GSE187515	scRNA-seq	104	Illumina MiSeq (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE279982	Methylation profiling (Array)	576	Infinium MethylationEPIC
C   GSE144329	ATAC-seq	96	NextSeq 550 (Homo sapiens)
GSE205204	RNA-seq	14	Illumina NovaSeq 6000 (Homo sapiens)
GSE125686	RNA-seq	62	Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE198339	scRNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE233747	scRNA-seq	40	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE220859	Chip-seq	11	Illumina NovaSeq 6000 (Homo sapiens)
GSE165708	RNA-seq	100	Illumina HiSeq 4000 (Homo sapiens)
C   GSE211651	Chip-seq;RNA-seq;PRO-seq	39	Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE198809	scRNA-seq	46	Illumina NovaSeq 6000 (Homo sapiens)
GSE68028	MeDIP-chip	1	NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C   GSE100376	ATAC-seq	24	Illumina NextSeq 500 (Homo sapiens)
GSE167211	RNA-seq	1	Illumina HiSeq 2000 (Homo sapiens)
GSE165132	RNA-seq	56	NextSeq 550 (Homo sapiens)
C   GSE100266	ATAC-seq;Chip-seq;RNA-seq	32	Illumina HiSeq 2500 (Homo sapiens)
C   GSE165703	ATAC-seq	82	Illumina HiSeq 4000 (Homo sapiens)
GSE246082	RNA-seq	6	Illumina HiSeq 4000 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE221688 - USP3 peak across samples

Peak Plot

> Dataset: GSE165705 - USP3 peak across samples

Peak Plot

> Dataset: GSE30738 - USP3 peak across samples

Peak Plot

> Dataset: GSE144329 - USP3 peak across samples

Peak Plot

> Dataset: GSE220859 - USP3 peak across samples

Peak Plot

> Dataset: GSE211651 - USP3 peak across samples

Peak Plot

> Dataset: GSE100376 - USP3 peak across samples

Peak Plot

> Dataset: GSE100266 - USP3 peak across samples

Peak Plot

> Dataset: GSE165703 - USP3 peak across samples

Peak Plot