HIV Target gene Detail Information

> FKBP5 Gene Search Result


Gene Information
Gene Name FKBP5
Gene ID 2289
Gene Full Name FKBP prolyl isomerase 5
Gene Alias AIG6|FKBP51|FKBP54|P54|PPIase|Ptg-10
Transcripts ENSG00000096060
Virus HIV
Gene Type protein-coding
HPA Location Info Nucleoplasm;Nucleoli fibrillar center, Cytosol;
Membrane Info Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q13451
HGNC ID HGNC:3721
OMIM ID 602623
Summary The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
Target gene [FKBP5] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000018 chr6 2448 142 106 2696 View
4000145 chr6 704 25 165 894 View
4000258 chr6 26 338 270 634 View
4001979 chr6 79 40 0 119 View
4002511 chr6 81 10 0 91 View
4002664 chr6 76 9 0 85 View
4003006 chr6 69 2 1 72 View
4003581 chr6 57 0 1 58 View
4005021 chr6 1 27 9 37 View
4005743 chr6 25 5 0 30 View
4005795 chr6 29 0 0 29 View
4006288 chr6 23 3 0 26 View
4006422 chr6 22 3 0 25 View
4006423 chr6 19 3 3 25 View
4006652 chr6 9 14 0 23 View
4006771 chr6 19 4 0 23 View
4007212 chr6 20 0 0 20 View
4008114 chr6 5 3 8 16 View
4008361 chr6 1 7 7 15 View
4008624 chr6 12 2 0 14 View
4009855 chr6 0 3 7 10 View
4013332 chr6 1 2 1 4 View
4013333 chr6 1 2 1 4 View
4014515 chr6 0 2 0 2 View
4015828 chr6 0 1 0 1 View
4016769 chr6 0 0 0 0 View

Target gene [FKBP5] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688
Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
GSE144332 RNA-seq 75 NextSeq 550 (Homo sapiens)
GSE157829 scRNA-seq 7 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165705
Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE202410 scRNA-seq 24 Illumina HiSeq 4000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE187515 scRNA-seq 104 Illumina MiSeq (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
C
  GSE144329
ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
S
  GSE198339
scRNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE233747 scRNA-seq 40 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE220859
Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651
Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE198809 scRNA-seq 46 Illumina NovaSeq 6000 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376
ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
GSE228078 scRNA-seq 12 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100266
ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703
ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE148796 scRNA-seq 4 Illumina NextSeq 500 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the query gene is differentially changed in the dataset, a feature/violin plot will be displayed.


> Dataset: GSE198339 - Gene expression in cell subsets