HIV Target gene Detail Information

> IKZF3 Gene Search Result


Gene Information
Gene Name IKZF3
Gene ID 22806
Gene Full Name IKAROS family zinc finger 3
Gene Alias AIO|AIOLOS|IMD84|ZNFN1A3
Transcripts ENSG00000161405
Virus HIV
Gene Type protein-coding
HPA Location Info Nucleoplasm;Cytosol;
Membrane Info Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q9UKT9
HGNC ID HGNC:13178
OMIM ID 606221
Summary This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
Target gene [IKZF3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000272 chr17 175 181 251 607 View
4000697 chr17 239 42 32 313 View
4001012 chr17 208 8 13 229 View
4001108 chr17 165 16 33 214 View
4001171 chr17 192 8 1 201 View
4001312 chr17 16 115 48 179 View
4001360 chr17 71 100 4 175 View
4001446 chr17 103 41 20 164 View
4001826 chr17 102 16 11 129 View
4001879 chr17 9 102 14 125 View
4002811 chr17 62 17 0 79 View
4002927 chr17 45 14 15 74 View
4003067 chr17 64 6 0 70 View
4003787 chr17 33 19 2 54 View
4003820 chr17 52 2 0 54 View
4004051 chr17 10 40 0 50 View
4004140 chr17 45 3 0 48 View
4004580 chr17 38 4 0 42 View
4004822 chr17 39 0 0 39 View
4005225 chr17 35 0 0 35 View
4005606 chr17 28 3 0 31 View
4005699 chr17 27 3 0 30 View
4006079 chr17 26 1 0 27 View
4006486 chr17 23 1 0 24 View
4007195 chr17 10 3 7 20 View
4007909 chr17 16 1 0 17 View
4008073 chr17 11 5 0 16 View
4008340 chr17 13 2 0 15 View
4008341 chr17 12 3 0 15 View
4008812 chr17 0 2 12 14 View
4009235 chr17 12 0 0 12 View
4009662 chr17 10 1 0 11 View
4009663 chr17 11 0 0 11 View
4009826 chr17 7 3 0 10 View
4010201 chr17 8 1 0 9 View
4010406 chr17 4 5 0 9 View
4010706 chr17 6 2 0 8 View
4010707 chr17 5 3 0 8 View
4010838 chr17 6 2 0 8 View
4011891 chr17 1 5 0 6 View
4012078 chr17 5 0 0 5 View
4012079 chr17 5 0 0 5 View
4012255 chr17 5 0 0 5 View
4012735 chr17 4 0 0 4 View
4012736 chr17 1 3 0 4 View
4013310 chr17 4 0 0 4 View
4015305 chr17 1 0 0 1 View

Target gene [IKZF3] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
GSE99737 RNA-seq 9 Illumina HiSeq 2500 (Homo sapiens)
GSE144332 RNA-seq 75 NextSeq 550 (Homo sapiens)
GSE157829 scRNA-seq 7 Illumina HiSeq 2500 (Homo sapiens)
GSE205320 scRNA-seq 5 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)
C
  GSE30738 		Chip-seq 2 Illumina Genome Analyzer II (Homo sapiens)
GSE262621 RNA-seq 70 Illumina NovaSeq 6000 (Homo sapiens)
GSE202410 scRNA-seq 24 Illumina HiSeq 4000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
E
  GSE162914 		RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
GSE187515 scRNA-seq 104 Illumina MiSeq (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE279982 Methylation profiling (Array) 576 Infinium MethylationEPIC
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
S
  GSE198339 		scRNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE233747 scRNA-seq 40 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE198809 scRNA-seq 46 Illumina NovaSeq 6000 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE165132 RNA-seq 56 NextSeq 550 (Homo sapiens)
S
  GSE228078 		scRNA-seq 12 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE162914 - IKZF3 expression across samples

Volcano Plot

Bar Plot