Gene Name	WNK1
Gene ID	65125
Gene Full Name	WNK lysine deficient protein kinase 1
Gene Alias	HSAN2|HSN2|KDP|PPP1R167|PRKWNK1|PSK|p65
Transcripts	ENSG00000060237
Virus	HIV
Gene Type	protein-coding
HPA Location Info	Cytosol;
Membrane Info	Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q9H4A3
HGNC ID	HGNC:14540
OMIM ID	605232
Summary	This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002548	chr12	81	8	0	89	View
4002780	chr12	31	49	0	80	View
4003842	chr12	35	8	10	53	View
4005299	chr12	17	5	12	34	View
4005479	chr12	11	15	6	32	View
4005516	chr12	9	23	0	32	View
4008221	chr12	16	0	0	16	View
4008873	chr12	10	3	0	13	View
4009368	chr12	9	2	1	12	View
4010276	chr12	7	2	0	9	View
4010277	chr12	7	2	0	9	View
4011039	chr12	7	0	0	7	View
4012050	chr12	3	2	0	5	View
4012208	chr12	2	2	1	5	View
4012209	chr12	2	2	1	5	View
4012441	chr12	5	0	0	5	View
4012700	chr12	3	1	0	4	View
4013570	chr12	0	3	0	3	View
4013848	chr12	2	1	0	3	View
4014348	chr12	2	0	0	2	View
4015236	chr12	1	0	0	1	View
4015780	chr12	1	0	0	1	View
4015952	chr12	0	0	0	0	View
4016178	chr12	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
C   GSE221688	Chip-seq;scATAC-Seq;scRNA-Seq	12	Illumina NovaSeq 6000 (Homo sapiens)
GSE99737	RNA-seq	9	Illumina HiSeq 2500 (Homo sapiens)
GSE144332	RNA-seq	75	NextSeq 550 (Homo sapiens)
GSE157829	scRNA-seq	7	Illumina HiSeq 2500 (Homo sapiens)
C   GSE165705	Chip-seq	30	Illumina NovaSeq 6000 (Homo sapiens)
GSE164264	RNA-seq	6	BGISEQ-500 (Homo sapiens)
C   GSE30738	Chip-seq	2	Illumina Genome Analyzer II (Homo sapiens)
GSE262621	RNA-seq	70	Illumina NovaSeq 6000 (Homo sapiens)
GSE202410	scRNA-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE128121	RNA-seq	16	Illumina HiSeq 4000 (Homo sapiens)
GSE162914	RNA-seq	211	Illumina HiSeq 2500 (Homo sapiens)
GSE187515	scRNA-seq	104	Illumina MiSeq (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE279982	Methylation profiling (Array)	576	Infinium MethylationEPIC
C   GSE144329	ATAC-seq	96	NextSeq 550 (Homo sapiens)
GSE205204	RNA-seq	14	Illumina NovaSeq 6000 (Homo sapiens)
GSE125686	RNA-seq	62	Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE198339	scRNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE233747	scRNA-seq	40	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE220859	Chip-seq	11	Illumina NovaSeq 6000 (Homo sapiens)
GSE165708	RNA-seq	100	Illumina HiSeq 4000 (Homo sapiens)
C   GSE211651	Chip-seq;RNA-seq;PRO-seq	39	Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE198809	scRNA-seq	46	Illumina NovaSeq 6000 (Homo sapiens)
GSE68028	MeDIP-chip	1	NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C   GSE100376	ATAC-seq	24	Illumina NextSeq 500 (Homo sapiens)
GSE167211	RNA-seq	1	Illumina HiSeq 2000 (Homo sapiens)
GSE165132	RNA-seq	56	NextSeq 550 (Homo sapiens)
GSE228078	scRNA-seq	12	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100266	ATAC-seq;Chip-seq;RNA-seq	32	Illumina HiSeq 2500 (Homo sapiens)
C   GSE165703	ATAC-seq	82	Illumina HiSeq 4000 (Homo sapiens)
GSE148796	scRNA-seq	4	Illumina NextSeq 500 (Homo sapiens)
GSE246082	RNA-seq	6	Illumina HiSeq 4000 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE221688 - WNK1 peak across samples

Peak Plot

> Dataset: GSE165705 - WNK1 peak across samples

Peak Plot

> Dataset: GSE30738 - WNK1 peak across samples

Peak Plot

> Dataset: GSE144329 - WNK1 peak across samples

Peak Plot

> Dataset: GSE220859 - WNK1 peak across samples

Peak Plot

> Dataset: GSE211651 - WNK1 peak across samples

Peak Plot

> Dataset: GSE100376 - WNK1 peak across samples

Peak Plot

> Dataset: GSE100266 - WNK1 peak across samples

Peak Plot

> Dataset: GSE165703 - WNK1 peak across samples

Peak Plot